FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
Surgery beyond bodies: Soul surgery and social surgery
Frontiers in Surgery, 2022 Bjørn Hofmann, Bjørn Hofmann
openaire +3 more sources
In the Hands of a Robot, From the Operating Room to the Courtroom: The Medicolegal Considerations of Robotic Surgery [PDF]
, 2023 Satvik N Pai +4 more
openalex +1 more source
Aging and Cancer, EarlyView.Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath +3 more
wiley +1 more source
Can PSA Predict Bone Metastasis amongst Newly Diagnosed Prostate Cancer Patients?
The Annals of African Surgery, 2018 Background: The decision as to when a bone scan is necessary in the staging of prostate cancer is controversial with different studies giving varying recommendations on the same subject.
D. Ojuka, MBChB, MMed, Surgery +2 more
doaj
Rural surgery as global surgery before global surgery
BMJ Global Health, 2022 Eric K Kim +3 more
openaire +3 more sources
NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao +10 more
wiley +1 more source
Can pretreatment platelet-to-lymphocyte and neutrophil-to-lymphocyte ratios predict long-term oncologic outcomes after preoperative chemoradiation followed by surgery for locally advanced rectal cancer? [PDF]
, 2022 Sang‐Hyun An, Ik Yong Kim
openalex +1 more source
Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham +7 more
wiley +1 more source
Clinical Practice Guidelines for ERAS in China(2021)(Ⅳ)
Xiehe Yixue Zazhi, 2021 Chinese Society of Surgery +1 more
doaj +1 more source