Results 171 to 180 of about 1,259,035 (250)

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source

Teamwork is the dream work: Hybrid team approaches for the treatment of stand-alone atrial fibrillationCentral Message

JTCVS Structural and Endovascular
Brian Lim, MD, Armin Kiankhooy, MD
doaj   +1 more source

Surgical ablation of atrial fibrillation with concomitant cardiac surgery: a state-of-the-art review. [PDF]

Eur J Cardiothorac Surg
Kowalewski M, Dąbrowski EJ, Kurasz A, Święczkowski M, Raffa GM, Kawczyński M, Aerts L, Kuźma Ł, Wańha W, Batko J, Litwinowicz R, Urbanowicz T, Stec S, Lorusso R, Hanke T, Maesen B, Meani P, Ronco D, Pilato M, Musumeci F, McCarthy P, Cox JL, Pannone L, Merino JL, Pürerfellner H, Badhwar V, La Meir M, de Asmundis C, Lip GYH, Suwalski P, Thoracic Research Centre, endorsed by the European Society of Cardiology Cardiovascular Surgery Working Group.   +31 more
europepmc   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source

Non-surgical ablation for breast cancer: an emerging therapeutic option

Non-surgical ablation is emerging as an alternative local therapy option for patients with early-stage breast cancer and encompasses two main types of percutaneous therapeutic procedures: radiofrequency ablation and cryoablation.
Chikako Yamauchi (6035825), Wonshik Han (6448), Ismail Jatoi (7539413), Takashi Inamoto (24557523), Masako Kataoka (818662), John R Benson (16266674), Takayuki Kinoshita (4594915), Masahiro Takada (818664), Masakazu Toi (181141)   +8 more
core   +1 more source

A commentary on "Thoracoscopic surgical ablation for atrial fibrillation patients with functional regurgitation: the treatment strategy prioritizing atrial fibrillation". [PDF]

Int J Surg
Chen X, Bao Y, Zhang Q.
europepmc   +1 more source

Using cell‐free RNA to identify B‐ and T‐cell clonality for diagnosis and monitoring of B‐ and T‐cell neoplasms

FEBS Open Bio, EarlyView.
Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Adam Albitar, Sally Agersborg, Ahmed Charifa, Pooja Phull, Noa Biran, David Vesole, Harsh Parmar, Andrew Pecora, Andrew Ip, Andre Goy, David Siegel, Maher Albitar   +11 more
wiley   +1 more source

Epicardial and hybrid surgical ablation of atrial fibrillation: 1-year follow-up outcomes of the EORP EHAFA registry. [PDF]

Europace
Vroomen M, La Meir M, Mokracek A, Doll KN, Folliguet TA, Lundqvist CB, Mont L, Peters NS, Pison L, EHAFAR Investigators .   +9 more
europepmc   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source