Results 51 to 60 of about 41,780 (280)

Identification of risk factors by systematic review and development of risk-adjusted models for surgical site infection [PDF]

, 2011
Background: Surgical site infections (SSIs) are complications of surgery that cause significant postoperative morbidity. SSI has been proposed as a potential indicator of the quality of care in the context of clinical governance and monitoring of the ...
Wilson, AP, Pearson, A. (Andrew), ZH Krukowski, Bruce, J, Krukowski, Zygmunt H., Gibbons, C., Pearson, A, Lamping, Donna Louise, Reeves, BC, AP Wilson, DL Lamping, J Wilson, Krukowski, ZH, Lamping, DL, J Carpenter, Krukowki, ZH, J Bruce, Carpenter, J., Gibbons, C, A Pearson, Wilson, J, Wilson, A. P. (A. Peter), BC Reeves, Reeves, B. C., Wilson, Jennie, RGN, C Gibbons, Bruce, J. (Julie), Carpenter, J   +27 more
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Intraoperative Redosing of Surgical Antibiotic Prophylaxis in Addition to Preoperative Prophylaxis Versus Single-dose Prophylaxis for the Prevention of Surgical Site Infection: A Meta-analysis and GRADE Recommendation

, 2022
OBJECTIVE: The aim of this study was to determine the effect of preoperative surgical antibiotic prophylaxis (SAP) with additional intraoperative redosing compared to single-dose preoperative surgical antibiotic prophylaxis on the incidence of surgical ...
Boermeester, Marja A., Boldingh, Quirine J. J., de Lange, Mats, de Jonge, Stijn W., Wolfhagen, Niels   +4 more
core   +1 more source

National surgical antibiotic prophylaxis guideline in Singapore

Annals of the Academy of Medicine, Singapore, 2022
Introduction: Institutional surgical antibiotic prophylaxis (SAP) guidelines are in place at all public hospitals in Singapore, but variations exist and adherence to guidelines is not tracked consistently. A national point prevalence survey carried out in 2020 showed that about 60% of surgical prophylactic antibiotics were administered for more than 24
Wei Teng Gladys, Chung, Humaira, Shafi, Jonathan, Seah, Parthasarathy, Purnima, Taweechai, Patun, Kai Qian, Kam, Valerie Xue Fen, Seah, Rina Yue Ling, Ong, Li, Lin, Robin Sing Meng, Choo, Pushpalatha, Lingegowda, Cheryl Li Ling, Lim, Jasmine Shimin, Chung, Nathalie Grace S Y, Chua, Tau Hong, Lee, Min Yi, Yap, Tat Ming, Ng, Jyoti, Somani   +17 more
openaire   +2 more sources

Control strategies to prevent total hip replacement-related infections: a systematic review and mixed treatment comparison

, 2014
Objective: To synthesise the available evidence and estimate the comparative efficacy of control strategies to prevent total hip replacement (THR)-related surgical site infections (SSIs) using a mixed treatment comparison.\ud Design: Systematic review ...
Cooper, N, H. Zheng (2057848), K. Merollini (7697756), Merollini, Katharina, Wilson, Jennie, Zheng, H, Berendt, T, Graves, Nicholas, Wilson, Jennie A., Nicola Cooper (698917), T. Berendt (7697759), Berendt, Tony, Zheng, Henry, Barnett, Adrian G., Sutton, A, Cooper, Nicola, J. Wilson (4917331), Barnett, A G, A. G. Barnett (7697753), Alex Sutton (11700), Graves, N, Wilson, J, N. Graves (7697762), Zhang, Henry, Sutton, Alex   +24 more
core   +1 more source

Nanocellulose Alleviates Intrahepatic Cholestasis of Pregnancy via Gut Microbiota‐Mediated Bile Acid Homeostasis

Advanced Science, EarlyView.
Nanocellulose, derived from microcrystalline cellulose (MCC) through sulfuric acid hydrolysis or mechanical grinding to produce CNC or CNF, was tested in a rat ICP model. Particularly, CNF improved gut microbiota composition, reduced secondary bile acid metabolism, and restored bile acid homeostasis through modulation of the gut–liver axis.
Muhua Yu, Hongjie Dai, Xiaocui Zhong, Qibin Li, Hui Yuan, Yang Yang, Daiyong Huang, Lei Zhang, Rui Ran, Tian He, Yuanzhi Huang, Silas Villas‐Boas, Sergey Tumanov, Richard D. Cannon, Boris Novakovic, Richard Saffery, Yuhao Zhang, Xiaojing Dong, Ting‐Li Han   +18 more
wiley   +1 more source

Autoimmune Encephalitis in Acute Care—Pathology, Diagnosis, and Management

Advanced Science, EarlyView.
ABSTRACT Autoimmune encephalitis (AE) is characterized by immune‐mediated inflammation of the brain parenchyma, presenting with various neurological syndromes, including but not limited to seizures, altered consciousness, neuropsychiatric symptoms, and movement disorders.
Suneesh Thilak, David Okoh, William Scotton, Shanika Samarasekera, Vikram Patil, Suresh Renukappa, Andrew Macduff, Subashini Suresh, Rajeev Krishnadas, Tonny Veenith   +9 more
wiley   +1 more source

Targeting Golgi–STING Signaling to Reprogram Innate and Adaptive Immunity for the Treatment of Implant‐Associated Infections

Advanced Science, EarlyView.
This study presents an ultrasound‐responsive nanoplatform, CS‐BT@MZ@NEs, with a BaTiO3/Mn‐Zif‐8 core and a chondroitin sulfate coating for Golgi targeting. By leveraging neutrophil hitchhiking, it enables targeted delivery to infection sites. Under ultrasound stimulation, CS‐BT@MZ@NEs generates ROS and modulates Golgi pH to activate cGAS–STING ...
Shicheng Huo, Naifeng Zhu, Zhuocheng Lyu, Yifei Liu, Zhenjiang Xu, Chun Zhou, Yaochao Zhao, Changgui Shi   +7 more
wiley   +1 more source

Antimicrobial Prophylaxis Reduces the Rate of Surgical Site Infection in Upper Gastrointestinal Surgery: A Systematic Review

Antibiotics, 2022
Surgical site infection occurs with high frequency in gastrointestinal surgery, contributing to the high incidence of morbidity and mortality. The accepted practice worldwide for the prevention of surgical site infection is providing single- or multiple ...
Luigi Marano, Ludovico Carbone, Gianmario Edoardo Poto, Natale Calomino, Alessandro Neri, Riccardo Piagnerelli, Andrea Fontani, Luigi Verre, Vinno Savelli, Franco Roviello, Daniele Marrelli   +10 more
doaj   +1 more source

Targeting DNGR‐1 with Fangchinoline Elevates Dendritic Cell Antigen Cross‐Presentation‐Mediated Antitumor Immunity in Melanoma

Advanced Science, EarlyView.
Fangchinoline is identified as a small‐molecule DNGR‐1 modulator that enhances dendritic‐cell cross‐presentation of tumor antigens. By engaging DNGR‐1 and activating Syk–Nox2 signaling, it promotes phagosomal ROS, antigen escape, MHC‐I presentation, and CD8+ T‐cell priming, thereby strengthening antitumor immunity and sensitizing tumors to PD‐1 ...
Yuan Liao, Zhenyang Ren, Jing Zhou, He Luo, Yuling Li, Dan Chen, Yuxiao Jiang, Canzhe Li, Mengyi Zheng, Anqi Li, Yao Wang, Yang Zhang, Dingye Wang, Yanjun Jiang, Jiangyong Gu, Biaoyan Du, Yafei Shi, Fang Liu, Jianyong Xiao, Kun Wang   +19 more
wiley   +1 more source

O uso profilático da amoxicilina em exodontias de terceiros molares impactados realizadas nas clínicas de Odontologia da UFSC: Estudo clínico randomizado duplo cego [PDF]

, 2013
TCC (graduação) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Odontologia.Este estudo clínico randomizado duplo cego objetivou avaliar o efeito da profilaxia com administração de amoxicilina pré-operatória no controle de infecção
Martins, Mariana Saideles
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