Results 171 to 180 of about 1,971,309 (276)

Atherosclerosis: From Pathogenesis to Therapeutic Interventions

MedComm, Volume 7, Issue 11, November 2026.
The diagram outlines the core mechanisms driving atherosclerosis, including endothelial dysfunction, inflammatory responses, phenotypic switching of smooth muscle cells, and the gut–vascular axis. It also presents the corresponding therapeutic approaches now under development, such as gene therapies, immunotherapies, and nanotechnology platforms ...
Enge Zhou, Chenxi Zhan, Yuting Li, Yi Zeng, Renfei Luo, Xin Ouyang, Shixing Liu, Renqiang Yang, Nianlong Yan, Long Jiang   +9 more
wiley   +1 more source

Re: Trans-catheter versus open surgical aortic valve replacement in severe symptomatic aortic stenosis. [PDF]

J Cardiothorac Surg
Keleş E, Rahman ÖF.
europepmc   +1 more source

Curcumin in the Treatment of Various Diseases: Mechanism of Action, Bioavailability, Therapeutic Effects, and Current Clinical Trials

MedComm, Volume 7, Issue 11, November 2026.
Curcumin, a naturally occurring polyphenol, exhibits significant anti‐inflammatory and antioxidant capabilities. This review elucidates the specific molecular mechanisms by which curcumin exerts therapeutic effects on various diseases, including neurological disorders, cardiovascular diseases, cancers, inflammatory disorders, and autoimmune diseases ...
Lin Wang, Qifei Pan, Wenjuan Long, Xinyao Li, Jianqin Mao, Sitong Zhou, Zihui Wang, Xuelian Zou, Yuqing She, Mingqin Shi, Yang Zhou, Jiarong Du, Zhongyang Hu, Xiaoman Lv, Yishu Chen, Dongdong Qin   +15 more
wiley   +1 more source

Clinical Outcomes of Transcatheter Versus Surgical Aortic Valve Replacement in Patients with Pure Native Aortic Regurgitation: A Systematic Review and Meta-Analysis. [PDF]

J Cardiovasc Dev Dis
Ke H, Wang S, Li J, Zhong G.
europepmc   +1 more source

Dual Gut Microbiota‐Dependent Mechanisms Underlying the Anti‐Atherosclerotic Effect of Tilianin

MedComm, Volume 7, Issue 11, November 2026.
(A) Tilianin reshapes the gut microbiota by increasing Bacteroidota, Akkermansia muciniphila, short‐chain fatty acids, and gut‐barrier integrity, while reducing Firmicutes, TMA, and TMAO. Gut microbial enzymes transform tilianin into acacetin and acacetin‐7‐O‐glucuronide.
Xuli Ruan, Ruyue Liu, Wenjiang Cao, Liping Wang, Mengran Guo, Zhongshan He, Yupei Zhang, Yaoyao Luo, Yuntao Gao, Chuansheng Huang, Yunli Zhao, Yong Yuan, Xiangrong Song, Xinchun Wang   +13 more
wiley   +1 more source

Transcatheter Versus Mechanical and Bioprosthetic Surgical Aortic Valve Replacement in Retrospective Patient Cohorts with Aortic Stenosis <75 Years. [PDF]

J Clin Med
Wang X, Zeng L, Ou Y, Zhang X, Peng Y, Wei X, Meng W, Feng Y, De Backer O, Chen M.   +9 more
europepmc   +1 more source

Development and evaluation of X‐ray lithophanes as test objects for interventional procedure simulation

Medical Physics, Volume 53, Issue 11, November 2026.
Abstract Background In the growing field of interventional radiology, emerging technologies implement the use of artificial intelligence (AI) to help tackle growing demands for treatment. Due to the anatomical differences in animals, volunteers offer the most realistic training and testing scenario, however safety considerations restrict rapid ...
Carlo Saija, Madeleine Dietrich, Federica Facente, Wen Wei, Campbell Littlefield, Mariia Kryshchuk, Pablo Aparicio‐Villar, Nassim Boudjatit, Antonia Pontiki, Richard James Housden, Eric Sejor, Kawal Rhode, Pierre Berthet‐Rayne   +12 more
wiley   +1 more source

The Senokine Gas6 Promotes Aortic Valve Calcification Through CaMKII–DRP1–Mediated Terminal Scission of Mitochondrial‐Derived Vesicles

Aging Cell, Volume 25, Issue 11, November 2026.
In age‐associated calcific aortic valve disease (CAVD), human valve tissues and calcifying human valvular interstitial cells (hVICs) exhibit senescence‐associated features, while calcifying hVICs hypersecrete mitochondrial‐derived vesicles (MDVs). Donut‐shaped mitochondria serve as physical platforms for MDV budding, whereas Gas6 promotes Ca2+–CaMKII ...
Yaoyu Zhang, Jialiang Zhang, Yanjiani Xu, Wenhua Lei, Fei Xu, Junli Li, Zisong Wei, Bo Su, Shuang Liu, Jing Zhou, Hongde Li, Junpeng Ran, Weiya Li, Tuerhongjiang Tuerdi, Xiaojiao Wang, Zhi Fang, Fangyang Huang, Mao Chen   +17 more
wiley   +1 more source

Machine Learning‐Based Classification of Right and Left Ventricular Outflow Tract Premature Ventricular Contractions

Annals of Noninvasive Electrocardiology, Volume 31, Issue 6, November 2026.
Machine‐learning analysis of ECG‐derived features and demographic variables enables accurate and interpretable differentiation between RVOT‐ and LVOT‐originating premature ventricular contractions. ABSTRACT Introduction Idiopathic premature ventricular contractions (PVCs) commonly originate from the right and left ventricular outflow tracts (RVOT and ...
Michail Botis, Dimitris Tsiachris, George G. Botis, Aristomenis Koumpanakis, Lamprini Iro Bartsioka, Ioannis Doundoulakis, Athanasios Kordalis, Christos‐Konstantinos Antoniou, Aikaterini‐Eleftheria Karanikola, George K. Matsopoulos, Konstantinos Tsioufis   +10 more
wiley   +1 more source

Prediction of coarctation of the aorta in fetuses with transposition of great arteries: Inverted ventricular discrepancy as a predictor of arch repair in TGA

Acta Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 11, Page 2359-2366, November 2026.
Fetal MV/TV ratio offers a simple and reproducible marker of AAO in TGA with a cutoff of ≥ 1.0 accurately predicting the need for arch repair. This simple echocardiographic marker improves prenatal risk stratification and surgical planning, facilitating prenatal counseling. Abstract Introduction Transposition of great arteries (TGA) with coarctation of
Cosimo Marco Campanale, Patrizio Moras, Serena Ventrella, Marco Masci, Luciano Pasquini, Alessandra Toscano   +5 more
wiley   +1 more source