Results 91 to 100 of about 790,755 (327)

Comparison of surgical conditions following premedication with oral clonidine versus oral diazepam for endoscopic sinus surgery: A randomized, double-blinded study

Journal of Anaesthesiology Clinical Pharmacology, 2016
Background and Aims: Endoscopic sinus surgery (ESS) provides a challenge and an opportunity to the anesthesiologists to prove their mettle and give the surgeons a surgical field which can make their delicate surgery safer,more precise and faster. The aim
Rohini V Bhat Pai, Santhoshi Badiger, Roopa Sachidananda, Santhosh Mysore Chandramouli Basappaji, Raghunath Shanbhag, Raghavendra Rao   +5 more
doaj   +1 more source

Pericytes change function depending on glioblastoma vicinity: emphasis on immune regulation

Molecular Oncology, EarlyView.
Pericytes alter their transcriptome depending on their proximity to the tumor core. In the tumor core, pericytes display a more active state with higher communication strength but with lower immune activation potential and a shift toward extracellular matrix production.
Carolina Buizza, Robert Carlsson, Coralie Gamper, Gayatri Chitale, Johan Bengzon, Gesine Paul   +5 more
wiley   +1 more source

Metabolic Comparison of One-Anastomosis Gastric Bypass, Single-Anastomosis Duodenal-Switch, Roux-en-Y Gastric Bypass, and Vertical Sleeve Gastrectomy in Rat [PDF]

, 2018
Background One-anastomosis gastric bypass (OAGB) and single-anastomosis duodenal switch (SADS) have become increasingly popular weight loss strategies. However, data directly comparing the effectiveness of these procedures with Roux-en-Y gastric bypass ...
Arble, Deanna M., Bozadjieva, Nadajda, Evers, Simon S., Frikke-Schmidt, Henriette, Lewis, Alfor, Myronovych, Andriy, Seeley, Randy J., Toure, Mouhamadoul Habib   +7 more
core   +1 more source

Assessment of Outcomes of the Modified Stoppa Approach in the Treatment of Acetabular Fractures: A Retrospective Cohort Study [PDF]

Ķazaķstannyṇ Klinikalyķ Medicinasy
Aims. To evaluate the efficacy of the modified Stoppa approach for surgical treatment of pelvic bone injuries based on clinical (sex distribution, fracture type), surgical (duration of operation, intraoperative blood loss, incision length, quality of ...
Nurgeldi Manap, Nagmet Mursalov, Mukhtar Abilmazhinov   +2 more
doaj   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

Undergraduate medical textbooks do not provide adequate information on intravenous fluid therapy: a systematic survey and suggestions for improvement [PDF]

, 2014
<b>Background</b><p></p> Inappropriate prescribing of intravenous (IV) fluid, particularly 0.9% sodium chloride, causes post-operative complications.
AD Shaw, AGMT Powell, AI Arieff, AN De Silva, Arfon GMT Powell, B Brandstrup, CJ Cook, DN Lobo, DN Lobo, G Chawla, G Marjanovic, GE Miller, GE Walker, General Medical Council, Gordon B Drummond, JA Lowell, OC Allenby-Smith, PJ Herrod, S Awad, S Scheingraber, SE Smith, Simon Paterson-Brown, SR Walsh, SR Walsh   +23 more
core   +3 more sources

Laparoscopic adjustable gastric banding – should a second chance be given? [PDF]

, 2020
Background: Obesity is a chronic relapsing-remitting disease and a global pandemic, being associated with multiple comorbidities. Laparoscopic adjustable gastric banding (LAGB) is one of the safest surgical procedures used for the treatment of obesity ...
Abraham, Jenny, Aylwin, Simon J. B., Barber, T. M., Dimitriadis, Georgios K., Ellis, Hugh L., Halder, Louise, Khan, Uzma, Leca, Bianca M., Menon, Vinod, Randeva, Harpal S., Shah, Neha, Shuttlewood, Emma   +11 more
core   +1 more source

Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies

FEBS Open Bio, EarlyView.
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa, Ilva Liekniņa, Svetlana Koteloviča, Ramona Petrovska, Gediminas Žvinys, Agne Petrosiute, Asta Zubrienė, Matīss Toms Laugalis, Vendija Skeltona, Juris Jansons, Madara Kreishmane, Edita Čapkauskaitė, Daumantas Matulis, Kaspars Tārs   +13 more
wiley   +1 more source

Complete and safe resection of challenging retroperitoneal tumors: anticipation of multi-organ and major vascular resection and use of adjunct procedures. [PDF]

, 2011
BackgroundRetroperitoneal tumors are often massive and can involve adjacent organs and/or vital structures, making them difficult to resect. Completeness of resection is within the surgeon's control and critical for long-term survival, particularly for ...
Eichler, Charles M, Nakakura, Eric K, Tseng, William W, Wang, Sam C, Warren, Robert S   +4 more
core   +6 more sources

Short peptide perturbs spermatogenesis via immune microenvironment dysregulation and mitochondrial imbalance

FEBS Open Bio, EarlyView.
In the blood–testis barrier, occludin is crucial for tight junctions. This study demonstrates that occludin‐targeting short peptides disrupt junction integrity, inducing immune cell infiltration, tumor necrosis factor‐α/interleukin‐6 secretion and mitochondrial dysfunction, ultimately triggering apoptosis.
Heng Wang, Xiaofang Tan, Deyu Chen
wiley   +1 more source