Microphysiological Systems for Comorbidity Studies: Chronic Kidney Disease and Osteoarthritis
This review highlights the potential of organ‐on‐a‐chip systems for studying comorbidities, using chronic kidney disease (CKD) and osteoarthritis (OA) as examples. It summarizes recent advances in kidney‐on‐a‐chip and joint‐on‐a‐chip models and discusses their current and potential application in investigating CKD, OA, and CKD‐OA comorbidity, aiming to
Mingying Han+7 more
wiley +1 more source
Analyzing the effectiveness and safety of arthroscopic suture anchor repair for anterior talofibular ligament in patients with ankle instability. [PDF]
Xu Z, Li Q, Ding X, Nie Y, Chen N.
europepmc +1 more source
Nanobody‐Decorated Lipid Nanoparticles for Enhanced mRNA Delivery to Tumors In Vivo
This study presents a targeted mRNA‐LNP platform engineered with anti‐PSMA nanobodies for prostate cancer therapy. Using different in vivo models, the authors demonstrate selective uptake and mRNA delivery in PSMA+ cancer cells. However, while targeting is enhanced, mRNA delivery efficacy is limited by tissue penetration, tumor necrosis, and immune ...
Pol Escudé Martinez de Castilla+16 more
wiley +1 more source
Effects of preoperative systemic administration of tranexamic acid alone on postoperative inflammation and pain in total hip arthroplasty: a retrospective cohort study. [PDF]
Mukasa F+4 more
europepmc +1 more source
Blood Loss Estimation on Surgical Sponges via Machine Learning and Rate-based Pixel Counting Method
Hüseyin Abacı, Fatih Soygazi
openalex +1 more source
Biologically-Based Notions About Uterine Bleeding During Myomectomy: Reasoning on Tradition and New Concepts. [PDF]
Tinelli A+8 more
europepmc +1 more source
Effect of Nanoparticle Rigidity on the Interaction of Stromal Membrane Particles with Leukemia Cells
Cell membrane nanoparticles made with stromal cells are prepared and used to target leukemia cells. Deposition of the cell membrane onto rigid silica cores leads to increased uptake both in leukemia cell lines and primary cells from patients. These results show that nanoparticle rigidity affects the interaction between cell membrane nanoparticles and ...
Sander de Weerd+8 more
wiley +1 more source