Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
Tranexamic acid reduces intraoperative occult blood loss and tourniquet time in obese knee osteoarthritis patients undergoing total knee arthroplasty: a prospective cohort study [PDF]
, 2018 Yutong Meng,1,* Zhirui Li,1,2,* Ke Gong,1 Xiao An,2 Jiyuan Dong,1 Peifu Tang1 1Department of Orthopedics, Chinese PLA General Hospital, Beijing, China; 2Department of Orthopedics, Chinese PLA General Hospital Hainan Branch, Sanya, China *These authors ...
Li Z +5 more
core
Ectopic pregnancy and blood loss during its surgical treatment [PDF]
, 2022 The bachelor's thesis deals with ectopic pregnancy and blood loss during its surgical treatment. The work is divided into a theoretical part and a research part.
Kolářová, Nikola
core
Assessment of Outcomes of the Modified Stoppa Approach in the Treatment of Acetabular Fractures: A Retrospective Cohort Study [PDF]
Ķazaķstannyṇ Klinikalyķ MedicinasyAims. To evaluate the efficacy of the modified Stoppa approach for surgical treatment of pelvic bone injuries based on clinical (sex distribution, fracture type), surgical (duration of operation, intraoperative blood loss, incision length, quality of ...
Nurgeldi Manap +2 more
doaj +1 more source
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
FEBS Open Bio, EarlyView.Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
Laboratory analyses for evaluation of platelet disorders and platelet concentrates [PDF]
, 2006 High quality of platelet analytics requires specialized knowledge and skills. It was applied to analyze platelet activation and aggregation responses in a prospective controlled study of patients with Finnish type of amyloidosis.
Javela, Kaija
core
Modeling the Measurements of Cochlear Microcirculation and Hearing Function after Loud Noise [PDF]
, 2011 Objective: Recent findings support the crucial role of microcirculatory disturbance and ischemia for hearing impairment especially after noise-induced hearing loss (NIHL).
Canis, Martin +11 more
core +1 more source
FEBS Open Bio, EarlyView.Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill +6 more
wiley +1 more source
ESTIMATED BLOOD LOSS IN CRANIOTOMY [PDF]
, 2017 Introduction: Estimated blood loss is an estimation of how much blood is loss during surgery. Surgical procedure requires a preparation of blood stock, but the demand for blood often larger than the actual blood used.
AM, Rachmawati +2 more
core +2 more sources
Blood level changes in total knee arthroplasty with and without a tourniquet
Revista Brasileira de OrtopediaOBJECTIVE: To evaluate the difference between the total blood loss in patients undergoing primary total knee arthroplasty with and without the use of tourniquet.
Marco Felipe Francisco Honorato de Barros +2 more
doaj +1 more source