Results 71 to 80 of about 537,725 (347)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

AUTOLOGOUS BLOOD TRANSFUSION IN ORTHOPEDIC AND ORAL SURGICAL PATIENTS [PDF]

, 1990
The procedure for autologous blood transfusion in the orthopedic and oral surgical patients in our university hospital is described. The collection of blood was begun from 3 weeks prior to the scheduled surgery.
Fumio, KOMATSU
core   +2 more sources

Effects of Anemia Treatment on the Accuracy of Measured Blood Loss in Pregnant Women Undergoing Cesarean Delivery: A Retrospective Study

Journal of Obstetric Anaesthesia and Critical Care
Context: There is no gold standard method for quantifying the volume of blood loss in surgical settings. Aims: To investigate the effects of anemia treatment on the differences between measured blood loss (MBL) and calculated blood loss (CBL) in pregnant
Mariko Sato, Mitsuru Ida, Sayuri Kawase, Yumiko Yamamoto, Masahiko Kawaguchi   +4 more
doaj   +1 more source

Comparative Study of Two Different Intravenous Doses of Tranexamic Acid with Placebo on Surgical Field Quality in Functional Endoscopic Sinus Surgery-A Randomised Clinical Trial [PDF]

Journal of Clinical and Diagnostic Research, 2019
Introduction: Intraoperative haemorrhage, which disrupts surgical patency, is a major obstacle for surgeons, especially in endoscopic sinus surgeries. Tranexamic acid is synthetic antifibrinolytic agent that binds competitively at lysine binding site on ...
Tamil Anbu Pannerselvam, Kodali V Rajesh kumar, Ranjith B Karthekeyan   +2 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Thromboelastographic assessment of the efficacy of rFVIIa in vitro and in vivo [PDF]

, 2008
Haemorrhage is a leading cause of death in both the military and civilian environs and blood loss from sites which are not easily accessible or do not lend themselves to direct physical compression to reduce blood loss contribute hugely to the ...
Wilson, Glen
core  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Association between hospital intraoperative blood transfusion practices for surgical blood loss and hospital surgical mortality rates. [PDF]

, 2012
OBJECTIVE: Blood loss during surgery is an important operative complication in patients undergoing major noncardiac surgery and may increase postoperative morbidity and mortality.
Vezeridis, Michael, Poses, Roy M, Eaton, Charles B, Trivedi, Amal, Friedmann, Peter D, Mor, Vincent, Smith, Tracy S, Uttley, Georgette, Wu, Wen-Chih, Henderson, William G   +9 more
core  

Use of tranexamic acid in scoliosis surgery

Хирургия позвоночника, 2016
Objective. To assess the effectiveness of tranexamic acid in the surgical correction of idiopathic scoliosis. Material and Methods. The study included a retrospective analysis of intraoperative and postoperative blood loss during surgical correction ...
Maya N. Lebedeva, Anastasia A. Ivanova, Aleksey V. Palmash, Ivan A. Statsenko, Aleksandr S. Vasyura   +4 more
doaj   +1 more source

Scoliotic deformity of the spine: epidemiology, classification, surgical treatment, prediction and correction of intraoperative blood loss

Медицинский совет, 2022
In this review are discussed the most important questions of diagnostics, surgical treatment and complications in the context of  anaesthesia choice and performance in  children and adolescents with different variants of  vertebral scoliotic deformity ...
I. V. Smirnov, G. E. Rojtberg, V. V. Lazarev, N. A. Buralkina, Z. K. Batyrova   +4 more
doaj   +1 more source