Risk Factors for Delirium After Spine Surgery in Extremely Elderly Patients Aged 80 Years or Older and Review of the Literature: Japan Association of Spine Surgeons with Ambition Multicenter Study [PDF]
Study Design:Retrospective database analysis.Objective:Spine surgeries in elderly patients have increased in recent years due to aging of society and recent advances in surgical techniques, and postoperative complications have become more of a concern ...
Abe Tetsuya+61 more
core +2 more sources
Methods of Blood Loss Quantification in Major Abdominal Surgery: A Narrative Review
Blood loss in major abdominal surgery is an essential parameter in the evaluation of strategies aimed at reducing perioperative bleeding. It is also an important parameter of quality of the surgical procedure, along with postoperative morbidity and ...
Ján Zajak+6 more
doaj +1 more source
Use of tranexamic acid in scoliosis surgery
Objective. To assess the effectiveness of tranexamic acid in the surgical correction of idiopathic scoliosis. Material and Methods. The study included a retrospective analysis of intraoperative and postoperative blood loss during surgical correction ...
Maya N. Lebedeva+4 more
doaj +1 more source
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton+17 more
wiley +1 more source
Major vascular injury resulting in uncontrolled bleeding is a catastrophic and often fatal complication of minimally invasive surgery. At the outset of these events, surgeons do not know how much blood will be lost or whether they will successfully ...
Dhiraj J. Pangal+14 more
doaj +1 more source
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski+19 more
wiley +1 more source
Calculation methods for intraoperative blood loss: a literature review
Intraoperative bleeding is a common issue in various surgical procedures, and the extent of bleeding significantly impacts the safety, efficacy, and prognosis of surgery. Therefore, accurate assessment of intraoperative blood loss and timely intervention
Yi-Min Lin, Chao Yu, Guo-Zhe Xian
doaj +1 more source
EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche+8 more
wiley +1 more source
Возможности снижения кровопотери при выполнении обширных резекций печени с применением газоструйной диссекции и «малообъемной» инфузионной терапии [PDF]
Рішення проблеми крововтрати при великих резекціях печінки є завданням як хірургів, так і анестезіологів. У статті наведені результати застосування методики «малооб’ємної» інфузійної терапії і вдосконаленою хірургічної техніки із застосуванням ...
Гусак, И.В.+2 more
core
Liver resections: complications and survival outcome [PDF]
none1noToday, liver resection represents one of the most effective therapies in the treatment of defined liver diseases, particularly for hepatocellular carcinomas, liver metastases and tumors originating from the bile ducts.
Grazi, Gian Luca
core +1 more source