Results 61 to 70 of about 1,451,625 (299)

Surgical complications associated with primary closure in patients with diabetic foot osteomyelitis

open access: yes, 2012
Background: The aim of this study was to determine the incidence of complications associated with primary closure in surgical procedures performed for diabetic foot osteomyelitis compared to those healed by secondary intention.
García Morales, Esther Alicia   +5 more
core   +1 more source

A Prospective, Single‐Center Trial Evaluating the Effectiveness of ClimateCare in the Acute Postoperative Management of Pressure Ulcers

open access: yesHealth Science Reports
Background and Aims Pressure ulcers (PU) are injuries to the skin and underlying tissue that can have significant morbidity with the presence of complications such as dehiscence and necrosis.
Stuti P. Garg   +7 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Transcatheter Vs. Surgical Closure of Atrial Septal Defects in Adults [PDF]

open access: yes, 2018
Percutaneous transcatheter device closure of secundum atrial septal defects (ASD) has now largely replaced surgical closure in most centres. The aim of this study was to compare results of transcatheter and surgical ASD closure in adults in Latvia during
Dombrovskis, Andis   +15 more
core   +1 more source

CLOSURE #8: Kieler e-Journal für Comicforschung [PDF]

open access: yes, 2021
Was verbindet zwei Panels, die nebeneinander stehen? Die Antwort auf diese Frage lautet zumeist ›eine Erzählung.‹ So verlangt zum Beispiel Scott McCloud, ›einige der Geheimnisse zu lüften, die die unsichtbare Kunst des Comic-Erzählens umgeben‹ (74).

core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Evaluation of the Ventricular Mechanical Dyssynchrony in Patients with Atrial Septal Defect [PDF]

open access: yesJournal of Tehran University Heart Center, 2009
Background: There is some evidence indicating improvement in myocardial performance after atrial septal defect closure, either device closure or surgical, but ventricular dyssynchrony has not been evaluated before and after surgical closure.
Maryam Esmaeilzadeh   +5 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Diagnosis and Management of Ventricular Septal Defects

open access: yesReviews in Cardiovascular Medicine
This review addresses the diagnosis and management of ventricular septal defects (VSDs). The VSDs are classified on the basis of their size, their number, and their location in the ventricular septum. Natural history of VSDs includes spontaneous closure,
P. Syamasundar Rao
doaj   +1 more source

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