Results 101 to 110 of about 2,681,091 (262)

Surgical approach and postoperative complications.

, 2015
PA, clinical pituitary apoplexy.* Pearson Chi-Square test.Surgical approach and postoperative complications.
Yiming Li (40290), Xuelan Zhao (130746), Haixia Chen (241394), Xiaoming Zhu (710820), Xuefei Shou (800497), Yao Zhao (317881), Yongfei Wang (608480), Wenjuan Jiang (800496), Cuiping Jiang (800494), Yan Wang (15435), Shiqi Li (800498), Qiongyue Zhang (800495), Hongying Ye (130762)   +12 more
core   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Surgical complications in gastric cancer patients preoperatively treated with chemotherapy: their risk factors and clinical relevance

, 2012
BACKGROUND: This study was designed to identify risk factors and oncological value for the development of postoperative complications after gastrectomy in gastric cancer patients with preoperative chemotherapy.
안지영, 형우진, 정재호, 김유민, 노성훈   +4 more
core  

Macular Surgery for Posterior Segment Complications of Uveitis

, 2008
■ Surgical management of uveitic macular complications utilizes standard vitreoretinal surgical techniques. ■ Medical management of uveitic macular complications utilizes intraocular corticosteroids and anti-angiogenic factors in common use for other ...
Davis, Janet L, Janet L. Davis
core   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

Interventions for the treatment of oral and oropharyngeal cancers: surgical treatment [PDF]

, 2006
This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: Primary objective To determine which surgical treatment modalities for oral/oropharyngeal cancer lead to the best outcome in terms of disease‐free survival, mortality
P Sloan, RJ Oliver, Conway, D., JE Clarkson, Clarkson, J. E., AM Glenny, Panel The CSROC Expert, Worthington, H. V.; id_orcid, M Macluskey, S Pavitt, Pavitt, S., Glenny, A. M.; id_orcid, HV Worthington, Oliver, Richard J., D Conway, Coulthard, Paul, Macluskey, M., Coulthard, Paul; id_orcid, Sloan, P.   +18 more
core   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Preventing and treating surgical site infection in patients with spinal metastatic disease [PDF]

, 2013
Surgery to remove secondary spinal tumours is often necessary to relieve symptoms associated with metastatic spinal cord compression (MSCC). However, such individuals are at high risk of surgical site infection (SSI).
Lui, Steve, Atkinson, Ross, Ousey, Karen, Ousey, Karen; id_orcid   +3 more
core  

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Aging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho, Quang Le, Ngoc Thach Tran, Van Viet Ung, Loc Vu   +4 more
wiley   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source