Results 61 to 70 of about 2,681,091 (262)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
BackgroundNutritional support after surgery is an essential part of recovery augmentation protocols, especially in high-risk surgical patients. Early enteral nutrition (EEN) within 24–48 h after surgery has been argued to enhance gastrointestinal ...
Biao Shi +6 more
doaj +1 more source
Barbara H Johnson,1 Stephen S Johnston,1 Pranjal Tewari,2 Mosadoluwa Afolabi,1 Walter Danker III3 1Epidemiology, Johnson & Johnson, New Brunswick, NJ, USA; 2Data Sciences, Mu Sigma, Bengaluru, Karnataka, India; 3Ethicon Franchise Health Economics and ...
Johnson BH +4 more
doaj
Complications of surgical treatment of cervical carcinoma
A total of 302 patients with stage Ib and IIa cervical carcinoma were submitted to radical hysterectomy and lymphadenectomy during the period from 1980 to 1994. The morbidity rate was 37.5% and the mortality rate 0.6%.
F.S. Abrão +3 more
doaj +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Comparison of recognition tools for postoperative pulmonary complications following thoracotomy [PDF]
Objectives To evaluate the recognition of postoperative pulmonary complications (PPC) following thoracotomy and lung resection using three PPC scoring tools. Design Prospective observational study.
Steyn, R. S. +26 more
core +1 more source
The ureterocolic fistula (UF) can be a rare but serious complication of abdomino-pelvic surgery, gynecological procedures, oncological or inflammatory conditions and, especially in colorectal surgery, it can be due to anastomotic leaks or iatrogenic ...
Salvatore Tramontano +8 more
doaj +1 more source
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Surgical Videos for Accident Analysis, Performance Improvement, and Complication Prevention
Conventional audit of surgical records through review of surgical results provides useful knowledge but hardly helps identify the technical reasons lying behind specific outcomes or complications. Surgical teams not only need to know that a complication
Adam Magos +3 more
core +1 more source

