Results 61 to 70 of about 2,681,091 (262)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Early nurse-initiated enteral nutrition and its impact on postoperative recovery and complication rates: a meta-analysis of surgical patient outcomes

open access: yesFrontiers in Nutrition
BackgroundNutritional support after surgery is an essential part of recovery augmentation protocols, especially in high-risk surgical patients. Early enteral nutrition (EEN) within 24–48 h after surgery has been argued to enhance gastrointestinal ...
Biao Shi   +6 more
doaj   +1 more source

Clinical and Economic Burden Associated with Prolonged Air Leaks Among Patients Undergoing Thoracic Resection: A Retrospective Database Analysis

open access: yesClinicoEconomics and Outcomes Research, 2023
Barbara H Johnson,1 Stephen S Johnston,1 Pranjal Tewari,2 Mosadoluwa Afolabi,1 Walter Danker III3 1Epidemiology, Johnson & Johnson, New Brunswick, NJ, USA; 2Data Sciences, Mu Sigma, Bengaluru, Karnataka, India; 3Ethicon Franchise Health Economics and ...
Johnson BH   +4 more
doaj  

Complications of surgical treatment of cervical carcinoma

open access: yesBrazilian Journal of Medical and Biological Research, 1997
A total of 302 patients with stage Ib and IIa cervical carcinoma were submitted to radical hysterectomy and lymphadenectomy during the period from 1980 to 1994. The morbidity rate was 37.5% and the mortality rate 0.6%.
F.S. Abrão   +3 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Comparison of recognition tools for postoperative pulmonary complications following thoracotomy [PDF]

open access: yes, 2011
Objectives To evaluate the recognition of postoperative pulmonary complications (PPC) following thoracotomy and lung resection using three PPC scoring tools. Design Prospective observational study.
Steyn, R. S.   +26 more
core   +1 more source

Case Report: Unusual presentation and atypical course of a case of ureterocolic fistula after anterior resection for sigmoid cancer

open access: yesFrontiers in Oncology
The ureterocolic fistula (UF) can be a rare but serious complication of abdomino-pelvic surgery, gynecological procedures, oncological or inflammatory conditions and, especially in colorectal surgery, it can be due to anastomotic leaks or iatrogenic ...
Salvatore Tramontano   +8 more
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Surgical Videos for Accident Analysis, Performance Improvement, and Complication Prevention

open access: yes, 2011
Conventional audit of surgical records through review of surgical results provides useful knowledge but hardly helps identify the technical reasons lying behind specific outcomes or complications. Surgical teams not only need to know that a complication
Adam Magos   +3 more
core   +1 more source

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