Results 41 to 50 of about 2,276,826 (242)

The effect of early versus delayed surgical debridement on the outcome of open long bone fractures at Bugando Medical Centre, Mwanza, Tanzania

Journal of Trauma Management & Outcomes, 2016
BackgroundUrgent surgical debridement of open long bone fractures is of paramount importance for prevention of subsequent infection. Due to limited information on the timing of this surgical procedure in Mwanza, Tanzania; the present study was conducted ...
Njee Nobert, Nyambura Moremi, Jeremiah Seni, Ramesh M Dass, I. H. Ngayomela, S. Mshana, J. Gilyoma   +6 more
semanticscholar   +1 more source

Self‐Powered Permeable Electronic Dressing for Exudate Management, Electrostimulation and Drug Delivery in Chronic Wound Healing

Advanced Functional Materials, EarlyView.
This study develops a self‐powered permeable electronic dressing (SPED) that synergistically integrates exudate management, electrical stimulation, and on‐demand drug delivery. The dressing effectively absorbs exudate while demonstrating potent antibacterial activity and accelerated tissue regeneration in diabetic mouse models, thereby promoting ...
Jiaheng Liang, Jingjing Fu, Jin Chai, Hongyu Jiang, Fan Chen, Yufei Zhang, Weihao Zhao, Xian Song, Zhihao Zhou, Lingtao Fang, Qiyao Huang, Peng Li, Zijian Zheng   +12 more
wiley   +1 more source

Medical Fabrics with Non‐Antibiotic, Supramolecular Antimicrobial Coatings: A Preventive Approach to Combat Biofilm Formation and Bacterial Dissemination

Advanced Healthcare Materials, EarlyView.
The study presents an antibiotic‐free strategy using medical fabrics coated with supramolecular assemblies of polyarginine and hyaluronic acid. These coatings showed strong antimicrobial and anti‐biofilm activity in vitro and in vivo, achieving major bacterial load reductions, including against MRSA.
Adjara Diarrassouba, Abdessalem Rekiki, Cécile Loubière, Sabine Kuchler‐Bopp, Lauriane Petit, Cynthia Calligaro, Derry Mercer, Aurore Gaudin, Naomi Canourgues, Emilie Adicéam, Benoit Beitz, Jeremy Welsch, Annabelle Vigué, Markus j. Kettel, Michael Karl, Chloé Guilbaud‐Chéreau, Philippe Lavalle, Nihal Engin Vrana, Skander Hathroubi   +18 more
wiley   +1 more source

Perianal necrotizing fasciitis: a case report and literature review

结直肠肛门外科
Necrotizing fasciitis has a low clinical incidence, and surgical debridement combined with broad-spectrum antibiotics represents the primary treatment approach.
Li Jingjing, Xu Xinyi, Zeng Yusha, Xue Yahong   +3 more
doaj   +1 more source

Wegener`s granulomatosis and mucoromycosis: A case study and review of literature

Advanced Biomedical Research, 2012
Mucormycosis is a fatal invasive infection which mostly involves diabetic or immunosuppressed patients. Early diagnosis, improving immunosuppression, systemic antifungal therapy, and surgical debridement are necessary for successful treatment.
Sayyed Mojtaba Abtahi, Mohammadreza Omrani, Mansoor Karimifar, Afrooz Eshaghian, Maryam Kachuei, Azarmidokht Momeni   +5 more
doaj   +1 more source

Efficacy of preemptive oral doses of acetaminophen and celecoxib for post-operative pain management after open-flap debridement: A randomised controlled study

Advances in Human Biology, 2020
Background: Open-flap debridement therapy often leads to frequent pain postoperatively. It has been reported that open-flap debridement causes pain in 79% of patients.
Santosh Kumar, Pratik Kamlesh Sanghavi, Parth Narendra Patel, Palak Hitesh Sonvane, Para Rakesh Dave, Vani Udaybhai Gor, Irfan Mohammed   +6 more
doaj   +1 more source

Surgical Diabetic Foot Debridement: Improving Training and Practice Utilizing the Traffic Light Principle

International Journal of Lower Extremity Wounds, 2019
Comprehensive management of a severe diabetic foot infection focus on clear treatment pathways. Including rapid, radical debridement of all infection in addition to intravenous antibiotics and supportive measures.
R. Ahluwalia, E. Vainieri, J. Tam, S. Sait, Aaditya Sinha, C. Manu, I. Reichert, V. Kavarthapu, M. Edmonds, Prashanth R. J. Vas   +9 more
semanticscholar   +1 more source

Oxygen and ROS Delivery for Infected Wound Healing and Future Prospects

Advanced Healthcare Materials, EarlyView.
Bacterial infection is a major driver of delayed wound healing and postsurgical readmissions; with rising antibiotic resistance, solid peroxide–releasing biomaterials offer sustained delivery of ROS/O2 for antimicrobial control and microenvironmental modulation.
Ayden Watt, Chably Rachella, Charlotte Jaloux, Joshua Vorstenbosch, Adam Hart, Michael Tanzer, Geraldine Merle, Jake Barralet   +7 more
wiley   +1 more source

A Rare Case of Fournier Gangrene after a Colostomy Closure

Translational Research in Urology, 2021
Introduction: Fournier gangrene is a surgical emergency that presents as necrotizing fasciitis. It mainly involved the genital and perineal regions. The predisposing factors are immunosuppression, diabetes mellitus, alcoholism, and surgical procedures ...
Abdolreza Mohammadi, Ali Tavoosian
doaj   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source