Results 41 to 50 of about 76,320 (256)

Perianal necrotizing fasciitis: a case report and literature review

结直肠肛门外科
Necrotizing fasciitis has a low clinical incidence, and surgical debridement combined with broad-spectrum antibiotics represents the primary treatment approach.
Li Jingjing, Xu Xinyi, Zeng Yusha, Xue Yahong   +3 more
doaj   +1 more source

Targeting a Myeloid–Regulatory B Cell Network Reverses Immune Paralysis in Periprosthetic Joint Infections

Advanced Science, EarlyView.
Periprosthetic joint infection establishes a sophisticated immunosuppressive network between CXCR4+ PMN‐MDSCs and Bregs, inducing profound CD8+ T cell paralysis. Alendronate effectively disrupts this CXCR4+ PMN‐MDSC–Breg axis by targeting STAT3, thereby restoring local immune surveillance.
Jintao Wu, Shutao Zhang, Yumin Lin, Juyang Jiao, Zhiwei Fu, Qimin Hong, Ziyi Zhao, Xinhua Qu, Fei Su, Bing Yue   +9 more
wiley   +1 more source

Beyond Potency: Emerging Determinants and Optimization Strategies Enhancing Therapeutic Efficacy of Adult Stem Cells

Advanced Science, EarlyView.
Adult stem cell therapy requires more than high in vitro potency. This review proposes a systems framework in which cell‐intrinsic programs, instructive microenvironmental cues, and pre‐/post‐delivery engineering are co‐designed under standardized translational rules.
Soo‐Rim Kim, Yun Jae Jung, Hwa‐Yong Lee   +2 more
wiley   +1 more source

Wegener`s granulomatosis and mucoromycosis: A case study and review of literature

Advanced Biomedical Research, 2012
Mucormycosis is a fatal invasive infection which mostly involves diabetic or immunosuppressed patients. Early diagnosis, improving immunosuppression, systemic antifungal therapy, and surgical debridement are necessary for successful treatment.
Sayyed Mojtaba Abtahi, Mohammadreza Omrani, Mansoor Karimifar, Afrooz Eshaghian, Maryam Kachuei, Azarmidokht Momeni   +5 more
doaj   +1 more source

Efficacy of preemptive oral doses of acetaminophen and celecoxib for post-operative pain management after open-flap debridement: A randomised controlled study

Advances in Human Biology, 2020
Background: Open-flap debridement therapy often leads to frequent pain postoperatively. It has been reported that open-flap debridement causes pain in 79% of patients.
Santosh Kumar, Pratik Kamlesh Sanghavi, Parth Narendra Patel, Palak Hitesh Sonvane, Para Rakesh Dave, Vani Udaybhai Gor, Irfan Mohammed   +6 more
doaj   +1 more source

A Plant Photoregulator‐Inspired S‐Type Heterojunction System for Diabetic Keratopathy via Tri‐Modal Light‐Driven Immunometabolic Reprogramming, Tissue Repair, and Antibacterial Activity

Advanced Science, EarlyView.
To address the multifaceted imbalance in diabetic keratopathy, a light‐responsive biomimetic platform (WCNx‐Rh2) is developed and integrates glucose degradation, immune modulation, and antibacterial defense through a designed heterojunction and screened immunomodulator. WCNx‐Rh2 reduces AGEs/ROS and inflammatory signaling, reprogramming dendritic cells
Mengzhen Zhao, Zhibin Zhou, Yuxuan Wei, Xiangfan Huang, Zhiyong Zhou, Jiaheng Chen, Haoxin Cheng, Xiaotian Hu, Xiaolei Wang   +8 more
wiley   +1 more source

Utility of VERSAJET™ hydrosurgery system in the surgical management of premature neonatal burns: a case report

Burns Open
Major burn injury in neonates is challenging to manage, both in terms of medical management due to low physiologic reserve and higher risk of sepsis and fluid overload, as well as surgical management in view of a thinner dermal layer prone to over ...
Xin Nee Ho, Gale Jue Shuang Lim, Tze Yean Kong, Yong Chen Por, Mei Ling Loh, Michael Ku-Hung Hsieh   +5 more
doaj   +1 more source

Cervical vertebral osteomyelitis secondary to Streptococcus equi infection in an adult horse - case report [PDF]

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2019
A 15-year-old, mixed breed, male horse was attended with a history of multiple abscesses in the cervical region with a three-year evolution. Upon admission, three fistulous tracts with drainage of purulent secretions in the cervical region, low body ...
J.M. Alonso, A.R. Ávila, L.M.C. Bueno, A. Hataka, V.M.V. Machado, A.L.G. Alves, M.J. Watanabe, C.A. Rodrigues, R.M. Barbosa, C.A. Hussni   +9 more
doaj   +1 more source

Complications and Clinical Outcomes Following Modified Endoscopic Denker's With Pyriform Aperture Preservation: A Prospective Analysis

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background The modified endoscopic Denker's (MED) approach provides access to all maxillary sinus (MS) walls for resection of various MS and retromaxillary pathologies, but the anteromedial maxilla has historically been resected. This study determined complication rates and outcomes following MED with pyriform aperture (PA) preservation ...
Yasser Almansour, Lane Donaldson, Khaled Kashlan, Swapna Vemuri, Jun Jin, John R. Craig   +5 more
wiley   +1 more source

A New Classification (Grading System) of Debridement in Diabetic Lower Limbs - an Improvization and Standardization in Practice of Diabetic Lower Limb Salvage Around the World

Medicine Science, 2014
Debridement is one of the most common and also a most underestimated surgical procedure performed by surgeons. For specialist like Podiatric surgeons and qualified wound care nurses, debridement of diabetic foot wounds has been an essential day to day ...
Amit Kumar C Jain
doaj   +1 more source