Results 41 to 50 of about 1,075,008 (249)

Impaired thrombin generation in Reelin-deficient mice: a potential role of plasma Reelin in hemostasis

, 2017
BackgroundReelin is a large extracellular glycoprotein that is present in the peripheral blood. That Reelin interacts with the coagulation components and elicits a functional role in hemostasis has not yet been elucidated.
Tseng, W. -L.;Chen, T. -H.;Huang, C. -C.;Huang, Y. -H.;Yeh, C. -F.;Tsai, H. -J.;Lee, H. -Y.;Kao, C. -Y.;Lin, S. -W.;Liao, H. -R.;Cheng, J. -C.;Ts, C. -P., 林淑華   +1 more
core   +1 more source

Graphene Layers as Functional Biomaterials. From Fabrication and Characterization to Biological Applications

Advanced Materials Interfaces, EarlyView.
Graphene layers are fabricated on Cu foil and transferred onto glass substrates to form double‐ and multi‐layer G‐glass. Raman spectroscopy confirms structural integrity, while SEM and fluorescence microscopy reveal favorable adhesion and spreading of L‐929 fibroblast cells.
Mariana Mihaela Apostol, Issam Boukhoubza, Daniela Oprea, Iulia Corina Ciobotaru, Catalin Negrila, Ionut Enculescu, Ecaterina Andronescu, Teodor Adrian Enache, Elena Matei   +8 more
wiley   +1 more source

Control of bleeding in surgical procedures: critical appraisal of HEMOPATCH (Sealing Hemostat)

Medical Devices: Evidence and Research, 2015
Kevin Michael Lewis,1 Carl Erik Kuntze,2 Heinz Gulle3 1Preclinical Safety and Efficacy, Baxter Healthcare Corporation, Deerfield, IL, USA; 2Medical Affairs, Baxter Healthcare SA, Zurich, Switzerland; 3Surgical Sciences and Engineering, Baxter Medical ...
Lewis KM, Kuntze CE, Gulle H
doaj  

Post-surgical Pancreatitis Masquerading as Recurrent Neuroendocrine Cancer [PDF]

, 2010
Neuroendocrine tumours of the pancreas can have a spectrum of behaviour from relatively benign to aggressive. Resection can result in cure although metastatic disease is described.
Oniscu, Anca, Stephen J Wigmore, Adair, Anya, Wigmore, Stephen J, Anya Adair, Anca Oniscu   +5 more
core   +1 more source

Magnetic Micro‐ and Nanorobots for Precision Thrombolysis: Design Strategies and Translational Challenges

Advanced Robotics Research, EarlyView.
Micro‐ and nanorobots for targeted thrombolysis. This perspective elaborates on the clinical indication of blood clot disorders and current limitations for treatment. As a novel, alternative solution, micro‐ and nanorobots can be used to treat and break down thrombi.
Joshua M. Mesfin, Yimo Yan, Nikola Cesarovic, Simone Schuerle   +3 more
wiley   +1 more source

Cell‐Based Biohybrid Micro/Nanorobots for Biotherapy

Advanced Robotics Research, EarlyView.
This review systematically evaluates cell‐based biohybrid micro/nanorobots (CB‐BMRs), highlighting their cell selection criteria, fabrication strategies, and diverse actuation modes. Furthermore, it surveys the promising therapeutic applications of CB‐BMRs in targeted cancer, thrombosis, and inflammation treatments, while comprehensively discussing ...
Lin Wang, Chenlu Liu, Yu Zhao, Chuanhua Li, Xuyang Chen, Shixiao Ding, Lizhou Dai, Guokun Wang, Tianlong Li, Jiaxin Li, Xuejia Liu, Haocheng Wang   +11 more
wiley   +1 more source

In Situ Genetic Engineering Facilitates MMP‐9‐Responsive TIMP1 Release Through Proteolytic Cleavage to Boost Diabetic Wound Healing

Advanced Science, EarlyView.
This study develops an MMP‐9‐responsive protein release system that transforms resident cells into drug depots through in situ genetic engineering. Anchored to the membrane, the therapeutic protein TIMP1 is selectively released upon MMP‐9 cleavage.
Yuan Zhang, Jiani Deng, Man Yee Cheung, Tingting Fu, Xufeng Qi, Dongqing Cai, Jianmin Sun, Gang Lu, Peng Shi, Wai‐Yee Chan, Xu Li, Hui Zhao   +11 more
wiley   +1 more source

Multidisciplinary Approach to the Challenge of Hemostasis

, 2010
A multidisciplinary panel consisting of experts chosen by the 2 chairs of the group representing experts in anesthesiology, blood banking, hematology, critical care medicine, and various Surgical disciplines (trauma, cardiac, pediatric, neurologic ...
Cooper, David, Hemphill, J. Claude, Hemostasis Summit Participants, Shander, Aryeh, Paidas, Michael J., Levy, Jerrold H., Kessler, Craig M., Holcomb, John B., Dutton, Richard P., Lawson, Jeffre H.   +9 more
core   +1 more source

Harnessing Phase Separation for the Development of High‐Performance Hydrogels

Advanced Science, EarlyView.
ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao, Yiming Ma, Baihao Shao, Molly M. Stevens   +3 more
wiley   +1 more source

Modulating Calcium Homeostasis via a Biomimetic Scaffold to Rescue Diabetic Ischemic Wounds

Advanced Science, EarlyView.
This strategy addresses impaired microcirculation and loss of extracellular matrix (ECM) guidance in diabetic wound healing. Musc@CP, a nanofibrous dressing combining an ECM‐mimetic chitosan‐pullulan scaffold with muscone, enhances perfusion by attenuating intracellular Ca2+ overload‐associated endothelial dysfunction.
Xiang Zheng, Mingmei Li, Jianjun Jiang, Yongchao Wang, Yaru Jia, Weilun Sun, Yi Yao, Pengli Gao, Linhua Zhang, Qi Guo, Guang Jia, Xing‐Jie Liang, Dunwan Zhu, Jinchao Zhang, Fangzhou Li   +14 more
wiley   +1 more source