Results 71 to 80 of about 140,507 (299)

2017 Robotic Instrument Segmentation Challenge [PDF]

, 2019
In mainstream computer vision and machine learning, public datasets such as ImageNet, COCO and KITTI have helped drive enormous improvements by enabling researchers to understand the strengths and limitations of different algorithms via performance ...
Allan, Max, Azizian, Mahdi, Bodenstedt, Sebastian, Duggal, Rahul, Herrera, Luis, Iglovikov, Vladimir, Kalavakonda, Niveditha, Kurmann, Thomas, Laina, Iro, Li, Wenqi, Luo, Huoling, Maier-Hein, Lena, Rieke, Nicola, Shvets, Alex, Speidel, Stefanie, Stoyanov, Danail, Su, Yun-Hsuan, Yang, Jian, Zhang, Zichen   +18 more
core   +1 more source

Expected exponential loss for gaze-based video and volume ground truth annotation

, 2017
Many recent machine learning approaches used in medical imaging are highly reliant on large amounts of image and ground truth data. In the context of object segmentation, pixel-wise annotations are extremely expensive to collect, especially in video and ...
BE Menze, H Shin, K Kamnitsas, L Maier-Hein, M Anthimopoulos, R Bermúdez-Chacón, T Hastie, V Cheplygina   +7 more
core   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

Psychometric adaptation of the hospital anxiety and depression scale as a self-rated suicide risk assessment instrument among Nigerian surgical patients

International Journal of Medicine and Health Development, 2023
Background: A key step in the detection of suicide risk in a primarily nonpsychiatric population will be the use of a simple brief self-reported psychometrically valid and reliable instrument that does not require prior training to administer. Objective:
Tolulope Opakunle, Olutayo Aloba, Chioma Nwozo, David-Daniel Adesanya, Oluwafisayo Adebimpe   +4 more
doaj   +1 more source

Comparative evaluation of instrument segmentation and tracking methods in minimally invasive surgery [PDF]

, 2018
Intraoperative segmentation and tracking of minimally invasive instruments is a prerequisite for computer- and robotic-assisted surgery. Since additional hardware like tracking systems or the robot encoders are cumbersome and lack accuracy, surgical ...
Agustinos, Anthony, Allan, Max, Bodenstedt, Sebastian, Du, Xiaofei, Garcia-Peraza-Herrera, Luis, Kenngott, Hannes, Kurmann, Thomas, Maier-Hein, Lena, Müller-Stich, Beat, Ourselin, Sebastien, Pakhomov, Daniil, Speidel, Stefanie, Stoyanov, Danail, Sznitman, Raphael, Teichmann, Marvin, Thoma, Martin, Vercauteren, Tom, Voros, Sandrine, Wagner, Martin, Wochner, Pamela   +19 more
core   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Surgical Audio Guidance: Feasibility Check for Robotic Surgery Procedures

Current Directions in Biomedical Engineering, 2020
In robot-assisted procedures, the surgeon controls the surgical instruments from a remote console, while visually monitoring the procedure through the endoscope.
Schaufler Anna, Illanes Alfredo, Maldonado Ivan, Boese Axel, Croner Roland, Friebe Michael   +5 more
doaj   +1 more source

Multimodal Magnetic Resonance and Near-Infrared-Fluorescent Imaging of Intraperitoneal Ovarian Cancer Using a Dual-Mode-Dual-Gadolinium Liposomal Contrast Agent. [PDF]

, 2016
The degree of tumor removal at surgery is a major factor in predicting outcome for ovarian cancer. A single multimodality agent that can be used with magnetic resonance (MR) for staging and pre-surgical planning, and with optical imaging to aid surgical ...
Annapragada, A, Anvari, B, Bankson, J, Bhavane, R, Kundra, V, Ravoori, MK, Singh, S, Sood, AK   +7 more
core   +2 more sources

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source