Results 141 to 150 of about 206,662 (256)

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Can viable bacteria be present in the surface of ready-to-use surgical instruments? [PDF]

Rev Col Bras Cir
Sauer CRO, Aoki FH, Kuboyama RH, Lima MRS, Saraiva IHBL, Silva CB, Fernandes Neto FA, Salles MJDC.   +7 more
europepmc   +1 more source

Effectiveness of the Glass Bead Sterilizer for Sterilizing Surgical Instruments. [PDF]

J Am Assoc Lab Anim Sci, 2022
Skiles B, Johnston NA, Hendrix GK, Hickman DL.   +3 more
europepmc   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

3D-printed patient-specific surgical instruments and implants: a technological leap in precision medicine. [PDF]

Ann Med Surg (Lond)
Khizar M, Zaib M, Haider S, Karimi H, Aminpoor H.   +4 more
europepmc   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Evaluation of the Ergonomics of Surgical Instruments Across Surgical Specialties: Responses From 459 Surgeons. [PDF]

Surg Innov
Elze M, Osterhoff G, Wermke A.
europepmc   +1 more source

Six Sigma can significantly reduce costs of poor quality of the surgical instruments sterilization process and improve surgeon and operating room personnel satisfaction. [PDF]

Sci Rep, 2023
Saporito A, Tassone C, Di Iorio A, Barbieri Saraceno M, Bressan A, Pini R, Mongelli F, La Regina D.   +7 more
europepmc   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Microcracks after apicoectomy with three surgical instruments: A comparative scanning electron microscopy study. [PDF]

J Conserv Dent Endod
Aucancela DAG, Carrillo K, Manosalvas MSP, Haro HPV.   +3 more
europepmc   +1 more source