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Surgical Excision Margins

Advances in Anatomic Pathology, 1999
The histopathologic status of excisional margins of malignant neoplasms has long been used as a potential indicator for recurrences and prognosis. The predictive ability of the margin, however, is far from satisfactory. Perhaps nowhere else in oncologic pathology has the significance of these margins been as intensively studied as in squamous cell ...
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Assessment of Surgical Margins

2020
In oral cavity SCCs, tumor margin status is an important prognostic factor. Achieving negative margins depends primarily on the surgeon skills and the accuracy of intraoperative margin assessment. Tumor margin of less than 5 mm is considered as close margin, while ≥5 mm is defined as negative margin. In patients with early-stage SCC of the oral cavity,
Ziv Gil, Shorook Na’ara
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The importance of surgical margins in pancreatic cancer

Journal of Surgical Oncology, 2015
Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive disease with a grim prognosis. Surgical resection offers the best chance for long‐term survival, yet recurrence rates are high and outcomes are poor. The influence of margin status in PDAC is controversial, as conflicting data have been plagued by a lack of standardization in margin ...
Cecilia G, Ethun, David A, Kooby
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Surgical Specimens and Margins

Cutis, 2022
Thomas N, Helm   +2 more
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The Art and Science of Surgical Margins for the Dermatopathologist

The American Journal of Dermatopathology, 2012
Basal cell carcinoma (BCC), squamous cell carcinoma (SCC) and primary cutaneous melanoma (PCM) are the major forms of skin cancer. Surgical excision is one of the most frequently utilized treatment modalities for these tumors.literature review.recommendations for lateral surgical excision margin (LEM) for BCCs is 4 mm for low-risk BCCs and Mohs surgery
Mara C, Weinstein   +3 more
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Surgical margins for excision of dermatofibrosarcoma protuberans

Journal of the American Academy of Dermatology, 1995
Dermatofibrosarcoma protuberans (DFSP) commonly recurs after standard surgical excision with a wide margin. No studies have been undertaken to objectively determine the appropriate surgical margins by measuring the extension of the subclinical tumor.Our purpose was to measure the subclinical extent of tumor in 20 patients with DFSP to determine ...
T L, Parker, J A, Zitelli
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Surgical excision margins for melanoma in situ

Journal of Plastic, Reconstructive & Aesthetic Surgery, 2014
Melanoma in situ (MIS) is a non-invasive lesion accounting for up to 27% of all melanomas by Coory et al. (2006).(1) MIS may be a precursor to invasive disease. The Lentigo Maligna (LM) subgroup of MIS carries upto a 4.7% lifetime risk of developing an invasive component by Agarwal-Antal et al.
S, Akhtar   +3 more
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The Effect of Contaminated Surgical Margins Revisited

Clinical Orthopaedics and Related Research, 2002
The current study was done to assess the oncologic outcomes after inadvertent intraoperative contamination in the treatment of musculoskeletal sarcomas, to determine the prognostic significance of these events. Forty-three patients with malignant lesions and either positive margins or intraoperative tumor penetration are included in the study.
Walter W, Virkus   +3 more
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Surgical Margin Assessment

2020
One of the goals in the management of primary malignant tumors is complete surgical excision of the tumor with adequate margins of normal surrounding tissue to minimize the risk of local recurrence. One of the pathologist’s tasks is to assess the surgical margin status. This chapter discusses the basic concepts of this task.
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Assessment of the Surgical Margins

2011
The local treatment of breast cancer has evolved significantly in the last 100 years. This was based on the notion that the removal of the entire breast and its lymphatic drainage area (axilla) would achieve not only local but also distant disease control.
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