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Assessment of Surgical Margins
2020In oral cavity SCCs, tumor margin status is an important prognostic factor. Achieving negative margins depends primarily on the surgeon skills and the accuracy of intraoperative margin assessment. Tumor margin of less than 5 mm is considered as close margin, while ≥5 mm is defined as negative margin. In patients with early-stage SCC of the oral cavity,
Ziv Gil, Shorook Na’ara
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[Positive surgical margins after radical prostatectomy].
Urologia, 2014Positive surgical margins (PSMs) in radical prostatectomy specimens are usually considered a negative prognostic parameter. However, their definition and the management of patients with PSMs remain unclear. The aim of the present review is to define pathological features of PSMs,to report their incidence and risk factors and to update PSMs prognostic ...
Galetti, Tommaso Prayer +3 more
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Personalizing surgical margins in retroperitoneal sarcomas
Expert Review of Anticancer Therapy, 2015Retroperitoneal sarcomas are a group of diseases that behave differently from one another. Well-differentiated liposarcomas have an indolent biology but show a tendency to recur locally even years after primary resection. Dedifferentiated liposarcomas are characterized by a very high local recurrence risk, while the metastatic risk mainly depends on ...
Dario, Callegaro +2 more
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Radical prostatectomy: Positive surgical margins matter
Urologic Oncology: Seminars and Original Investigations, 2013A positive surgical margin (PSM) in the radical prostatectomy (RP) specimen is associated with biochemical recurrence (BCR) and the need for adjuvant radiation therapy, and is a surrogate for surgical quality. We review the available data describing the identification, anatomy, and management of PSM after RP.A PubMed search (using English language as a
Joshua J, Meeks, James A, Eastham
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Positive Surgical Margins: Race or Surgeon?
European Urology, 2015The present study by Jalloh et al. published in this month’s issue of European Urology aimed to investigate the influence of racial variations on pathologic outcome after radical prostatectomy (RP) for low-risk prostate cancer (PCa) patients. The positive surgical margin (PSM) rate was significantly higher in the African American group (31%) than in ...
Alexandre R, Zlotta, Cynthia, Kuk
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The Many Faces of Surgical Margins
American Journal of Clinical Oncology, 2007Most variables associated with survival after cancer surgery are fixed when we see the patient. One variable over which we have control is the surgical margin. We begin by reviewing the definitions of a positive surgical margin, and then explore potential inaccuracies in obtaining a biopsy and reasons for recurrence after obtaining a free surgical ...
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Towards a process-based understanding of rifted continental margins
Nature Reviews Earth & Environment, 2023J S Collier, Hopper, John R
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