Results 51 to 60 of about 158,168 (261)

Clinicopathologic correlations in eyes enucleated after uveal melanoma resection with positive surgical margins

Indian Journal of Ophthalmology, 2007
We identified three eyes that had undergone enucleation after transscleral resection of uveal melanoma. Two enucleated eyes with microscopically positive margins of resection exhibited no evidence of residual melanoma and these patients were alive ...
Khalifa Yousuf, Aaberg Jr Thomas, Aaberg Sr Thomas, Grossniklaus Hans   +3 more
doaj  

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Combined cross-sectional and tangential margin evaluation of different tumor types in dogs and cats

Frontiers in Veterinary Science
IntroductionHistological evaluation of tumors involves tumor diagnosis and assessment of surgical margins to determine whether they are free (clean) or infiltrated (dirty) by neoplastic cells.
Simona Vincenti, Leonore Aeschlimann, Anna Brunner, Beatriz Vidondo, Vincent Wavreille, Ludmila Bicanova, Sara Soto   +6 more
doaj   +1 more source

Treatment Outcomes of Locally Advanced Squamous Cell Carcinoma of the Ethmoid Sinus Treated with Anterior Craniofacial Resection or Chemoradiotherapy

Case Reports in Oncology, 2017
We retrospectively analyzed 14 patients with locally advanced squamous cell carcinoma of ethmoid sinus (LASCC-ES) for the feasibility of anterior craniofacial resection (ACFR).
Takeharu Ono, Norimitsu Tanaka, Hirohito Umeno, Kiyohiko Sakata, Motohiro Morioka, Yoko  Ohmaru, Hideaki Rikimaru, Noriyuki Koga, Kensuke Kiyokawa, Shun-ichi Chitose, Buichiro  Shin, Takeichiro Aso, Hidehiro Etoh, Toshi Abe   +13 more
doaj   +1 more source

Expression of Ki-67, Cornulin and ISG15 in non-involved mucosal surgical margins as predictive markers for relapse in oral squamous cell carcinoma (OSCC).

PLoS ONE, 2021
BackgroundLocal relapse of oral squamous cell carcinoma in non-involved mucosal surgical margins indicated possibility of field alteration in the margins, which could be predicted with certain biomarkers. The objectives were to evaluate the expression of
Padmanabha Kumar Govindaraj, Thomas George Kallarakkal, Rosnah Mohd Zain, Wanninayake Mudiyanselage Tilakaratne, Huai Lin Lew   +4 more
doaj   +1 more source

Surgical margins in the veterinary cancer patient [PDF]

Veterinary and Comparative Oncology, 2017
AbstractIn veterinary oncologic specimens, histopathology is the gold standard for determining adequacy of excision. Despite limitations of this technique, the pathologist's interpretation of margin status significantly impacts patient management, including indications for adjuvant therapy.
M. Milovancev, D. S. Russell
openaire   +2 more sources

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Cavity Shave Margins in Breast Conservative Surgery a Strategy to Reduce Positive Margins and Surgical Time

Current Oncology
Background: Resection of additional tissue circumferentially around the cavity left by lumpectomy (cavity shave) was suggested to reduce rates of positive margins and re-excision. Methods: A single center retrospective study which analyzed margins status,
Gianluca Vanni, Marco Pellicciaro, Giulia Renelli, Marco Materazzo, Amir Sadri, Valentina Enrica Marsella, Federico Tacconi, Sebastiano Angelo Bastone, Benedetto Longo, Giordana Di Mauro, Valerio Cervelli, Massimiliano Berretta, Oreste Claudio Buonomo   +12 more
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Surgical Margin Status after Breast Conservation Surgery at Aga Khan University Hospital Nairobi

The Annals of African Surgery, 2018
Background: The conservation of the breast in a woman after diagnosis of breast cancer plays a vital role in the overall management of the patient. While the cosmetic outcome enhances the patients’ self-image, assurance of clear margins is essential in ...
Riogi B, Wasike R
doaj