Results 191 to 200 of about 1,131,831 (245)
Cancer Science, EarlyView.Single CTC analysis revealed extensive inter‐ and intra‐patient heterogeneity of PI3K/AKT/PTEN pathway alterations in HR+/HER2− metastatic breast cancer, capturing both SNVs and CNAs, including PTEN loss‐of‐function events. Longitudinal CTC profiling also uncovered dynamic clonal evolution, highlighting its potential to complement tissue and ctDNA ...
Tania Rossi +10 more
wiley +1 more source
Update on Menopause Hormone Therapy; Current Indications and Unanswered Questions
Clinical Endocrinology, EarlyView.ABSTRACT Objective To provide clinicians involved in managing menopause with a summary of current evidence surrounding menopause hormone therapy (MHT). Design The authors evaluate and synthesize existing pooled evidence relating to MHT's clinical indications, efficacy, and safety and explore the limitations of existing data. Patients The review focuses
Annice Mukherjee, Susan R. Davis
wiley +1 more source
Lifestyle Management in Menopause: A Systematic Review of Women With Premature Ovarian Insufficiency
Clinical Endocrinology, EarlyView.ABSTRACT Objective Premature ovarian insufficiency (POI), the loss of ovarian function before age 40, increases the risk of cardiovascular disease, low bone mineral density, dementia and psychological distress. Lifestyle interventions reduce chronic disease risk in other populations and, with hormone therapy, may improve health outcomes in POI.
Ladan Yeganeh +4 more
wiley +1 more source
Comparison of transitional vs surgical menopause on monoamine and amino acid levels in the rat brain. [PDF]
Mol Cell Endocrinol, 2018 Long T +6 more
europepmc +1 more source
Clinical Oral Implants Research, EarlyView.ABSTRACT Background Postmenopausal osteoporosis associated with cafeteria diet and bisphosphonate therapy may impair peri‐implant bone repair. Therefore, strategies to enhance osseointegration are needed. Aim This study investigated whether teriparatide‐coated implant surfaces enhance osseointegration in a rodent model of estrogen deficiency (OVX) and ...
Ana Cláudia Ervolino da Silva +9 more
wiley +1 more source
Surgical Menopause and Frailty Risk in Community-Dwelling Older Women: Study of Osteoporotic Fractures. [PDF]
J Am Geriatr Soc, 2018 Huang G +6 more
europepmc +1 more source
Diabetes, Obesity and Metabolism, EarlyView.ABSTRACT Background The interplay between obesity and physical performance in women is poorly understood, especially before the fifties. Objective To assess associations between weight gain from early to mid‐adulthood and midlife performance‐based physical function.
Leticia W. Ribeiro +3 more
wiley +1 more source
Menopause in the French Workplace: Embodiment, Regulation, and Digital Resistance
Gender, Work &Organization, EarlyView.ABSTRACT Menopause remains largely invisible in workplace discussions, despite its impact on women's wellbeing and careers. Shaped by norms that prioritize youth, bodily control, and constant productivity, menopause is often treated as a personal health issue rather than an organizational concern.
Lara Bertola +2 more
wiley +1 more source
Gender, Work &Organization, EarlyView.ABSTRACT Infertility predominantly affects people of working age, yet the experience of pursuing treatment while in employment rarely enters the workplace as a legitimate concern. Drawing on a longitudinal autoethnography of fertility treatment undertaken alongside an early academic career in Ireland between 2017 and 2024, and informed by policy, legal,
Valentina Paolucci
wiley +1 more source