Results 91 to 100 of about 624,915 (305)

Processing of surgical specimens with forensic evidence: lesson's learned in pathology from the Boston Marathon Bombing.

, 2023
CONTEXT: Following the Boston Marathon bombings in April 2013, pathology departments at hospitals across Boston, Massachusetts received numerous amputated limbs, as well as other surgical specimens from trauma surgeries.
Remick, DG, Ceddroth, T, Byrne-Dugan, CJ, Deshpande, A   +3 more
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Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Selective breast/gynecologic pathology fellowship training in the United States: Experience of program directors

Published data on combined breast and gynecologic [breast/gyn] surgical pathology fellowship training programs are limited. Our study aimed to survey the landscape of such fellowships in the United States (US), including specific information about their ...
Bhargava, Rohit, Hagemann, Ian S, Khan, Ashraf, Cosar, Ediz F, Fadare, Oluwole, Jorns, Julie M, Ali, Muhammad, Khoury, Thaer, Desouki, Mohamed Mokhtar, Karabakhtsian, Rouzan G, Klein, Molly E, Clark, Jennifer L, Deavers, Michael T, Pinto, Andre   +13 more
core   +2 more sources

Microscopic thymoma: A report of four cases with review of literature

Indian Journal of Pathology and Microbiology, 2011
Context: Thymectomy is an effective therapy for patients with myasthenia gravis, and the lesions usually identified are lymphoid hyperplasia and thymomas. Nodular epithelial proliferations, termed as microscopic thymoma, are rare.
Pradeep Vaideeswar
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Clinical and translational research on cancer of the stomach and gastroesophageal junction: A pathologist's view

Clinical and Translational Discovery
Adenocarcinomas of the stomach and gastroesophageal junction remain one of the most common malignant tumours in humans worldwide, often with a poor prognosis.
Christoph Röcken
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

PROFESSOR S. R. MIROTVORTSEV - MANAGING FACULTY OF SURGICAL PATHOLOGY WITH DESMURGY AND THE DOCTRINE ABOUT DISLOCATIONS AND CRISESOF MEDICAL FACULTY OF SARATOV UNIVERSITY [PDF]

Саратовский научно-медицинский журнал, 2008
In 2008 130 years have passed since birthday of the well-known Russian surgeon and academician Sergey Romanovich Mirotvortsev, who had made an important contribution to organization of public health and formation of surgical service in Saratov region ...
P.V. Glybochko, G.A. Bluvshtejn
doaj  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Personal Papers (MS 80-0002)

, 1955
Letter from A. H. Blackshear, Jr., to Surgical Pathology enclosing a check for $10.00 covering he statement of July 27, 1955 for the account of Mrs.
Blackshear, A. H., Jr.
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