Results 81 to 90 of about 2,133,363 (299)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Pathology of Common Nonneoplastic Orthopedic Diseases

open access: yes
The tissues removed in the surgical treatment of nonneoplastic musculoskeletal diseases represent the most frequent source of surgical pathology specimens in bone and soft tissue pathology.
Rosenberg, Andrew E.   +1 more
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

AgNOR volumes in normal and malignant colorectal and epithelium

open access: yes, 1994
The Annual Meeting of the Hong Kong Division of the International Academy of Pathology, 1993. In International Journal of Surgical Pathology, 1994, v.
Dockery, P, Morais, M, White, FH
core   +1 more source

Computer-aided Monitoring of Surgical Pathology Workflow [PDF]

open access: yes, 2009
ObjectiveTo explore the feasibility of computer-aided monitoring of surgical pathology workflow.Materials and MethodsWe analyzed the four subprocesses in the surgical pathologic process: (1) arranging surgical pathology examination to receipt of the ...
Chien, Sou-Hsin   +5 more
core   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Preanalytic determinants of surgical pathology practice in Uyo

open access: yesSaudi Journal for Health Sciences, 2018
Context: The aim of this study is to evaluate the various determinants of the preanalytic phase of surgical pathology (SP) in Uyo. Materials and Methods: This is a cross-sectional descriptive study (prospective) of all SP specimens that were sent to the ...
Chukwuemeka Charles Nwafor, Kanu Obioha
doaj   +1 more source

Pathology without microscope: From a projection screen to a virtual slide

open access: yes, 2020
We have witnessed successive stages since the Seventies in the advancements towards digital pathology. We agree with Dr Pallua et al on the tremendous changes that are taking place in pathology, all leading toward greater role of digitalization in the ...
Montironi, Rodolfo   +5 more
core   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

A Standardized Pathology Report for Gastric Cancer [PDF]

open access: yes, 2017
Background and Methods : The Gastrointestinal Pathology Study Group of the Korean Society of Pathologists developed a standardized pathology reporting format for gastric cancer in collaboration with the Korean Gastric Cancer Association.
김호근
core  

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