Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Endometriosis – especially surgical pathology?
Гинекология, 2013 The application of the combined hormonal contraceptives in the preventive maintenance of disease and the successful fight with the most common clinical manifestations of endometriosis, namely, with the syndrome EAPP (endometriosis associated pelvic pain):
A L Tikhomirov
doaj
Surgical Pathology Report: Amelogenesis imperfecta
, 2022 Surgical Pathology Report of amelogenesis imperfecta ...
A A A S Adikari (13154171) +1 more
core +1 more source
Implementation of a Quality and Patient Safety Curriculum for Pathology Residency Training [PDF]
, 2021 Quality and Patient Safety education for resident physicians is necessary to prepare them for independent practice and to meet accreditation requirements.
Chute, Deborah J. +2 more
core +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Unmasking the “Braided” Bowel: Chronic Intestinal Pseudo-Obstruction—A Case Report
DiagnosticsBackground and Clinical Significance: Chronic intestinal pseudo-obstruction (CIPO) clinically presents as a mechanical obstruction. When patients present with signs of impending ischemia, emergency exploratory laparotomy is indicated.
Chun-Heng Hung +2 more
doaj +1 more source
Performance of a web-based method for generating synoptic reports
Journal of Pathology Informatics, 2017 Context: The College of American Pathologists (CAP) requires synoptic reporting of all tumor excisions. Objective: To compare the performance of different methods of generating synoptic reports.
Megan A Renshaw +7 more
doaj +1 more source
Idiopathic scrotal calcinosis: an unusual skin disorder [PDF]
Revista Brasileira de Cirurgia Plástica, 2019 Idiopathic scrotal calcinosis is a rare benign entity. Patients affected by scrotal calcinosis usually do not have other associated symptoms. We report the case of a 30-yearold man with several calcified nodules in the scrotal sac with onset at age 15 ...
Fernando Passos da-Rocha +3 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
AECVP and SCVP 2009 recommendations for training in cardiovascular pathology.
, 2010 ardiovascular disease is of continuing importance as the result of a growing burden of risk factors in both developing and developed countries and the increasing number of elderly people worldwide.
SHEPPARD MN +23 more
core +1 more source