Results 101 to 110 of about 2,133,363 (299)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Microscopic thymoma: A report of four cases with review of literature

Indian Journal of Pathology and Microbiology, 2011
Context: Thymectomy is an effective therapy for patients with myasthenia gravis, and the lesions usually identified are lymphoid hyperplasia and thymomas. Nodular epithelial proliferations, termed as microscopic thymoma, are rare.
Pradeep Vaideeswar
doaj   +1 more source

Voice Recognition Technology Implementation in Surgical Pathology: Advantages and Limitations

, 2011
Context.—Voice recognition technology (VRT) has been in use for medical transcription outside of laboratories for many years, and in recent years it has evolved to a level where it merits consideration by surgical pathologists.Objective.—To determine the
Meenakshi Singh, Timothy R. Pal
core   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Clinical and translational research on cancer of the stomach and gastroesophageal junction: A pathologist's view

Clinical and Translational Discovery
Adenocarcinomas of the stomach and gastroesophageal junction remain one of the most common malignant tumours in humans worldwide, often with a poor prognosis.
Christoph Röcken
doaj   +1 more source

Pathology reporting of neuroendocrine tumors: application of the Delphic consensus process to the development of a minimum pathology data set.

, 2010
Epithelial neuroendocrine tumors (NETs) have been the subject of much debate regarding their optimal classification. Although multiple systems of nomenclature, grading, and staging have been proposed, none has achieved universal acceptance.
Chetty, R, Adsay, NV, Washington, Mary Kay, Yao, J, Klimstra, David S., Moss, Steven F., Klimstra, DS, Yao, James, Rindi, Guido, Tang, Laura H., Chetty, Runjan, Kidd, M, Robert, ME, Öberg, Kjell,, Gönen, M, Tzen, Chin-Yuan, O'Toole, Dermot, Kulke, MH, Jensen, RT, Moss, SF, Wiedenmann, B, Oberg, K, Deshpande, V, Modlin, Irvin R., Lloyd, RV, Deshpande, Vikram, Rindi, G, Tang, LH, Jensen, Robert T., Modlin, IR, Adsay, N. Volkan, Kidd, Mark, O'Toole, D, Tzen, CY, Gönen, Mithat, Kulke, Matthew H., Robert, Marie E., Moran, C, Suster, S, Suster, Saul, Washington, MK, Moran, Cesar, Wiedenmann, Betram, Lloyd, Ricardo V.   +43 more
core   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

PROFESSOR S. R. MIROTVORTSEV - MANAGING FACULTY OF SURGICAL PATHOLOGY WITH DESMURGY AND THE DOCTRINE ABOUT DISLOCATIONS AND CRISESOF MEDICAL FACULTY OF SARATOV UNIVERSITY [PDF]

Саратовский научно-медицинский журнал, 2008
In 2008 130 years have passed since birthday of the well-known Russian surgeon and academician Sergey Romanovich Mirotvortsev, who had made an important contribution to organization of public health and formation of surgical service in Saratov region ...
P.V. Glybochko, G.A. Bluvshtejn
doaj  

Mesothelial Cells Within Vascular Transformation of Mediastinal Lymph Node Sinuses: An Unusual Benign Collision Mimicking Colliding Malignancies [PDF]

, 2016
Vascular transformation of lymph node sinuses represents a rare benign entity mimicking malignant counterparts such as nodal Kaposi sarcoma. The presence of mildly atypical benign mesothelial cells within nodal sinuses raises the possibility of ...
Tawil, Ayman N., Boulos, Fouad I., Jabbour, Mark N.   +2 more
core   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source