Results 111 to 120 of about 2,278,162 (304)

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

open access: yesMolecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan   +8 more
wiley   +1 more source

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

open access: yesMolecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara   +10 more
wiley   +1 more source

Review of 253 cases of significant pathology in 7,910 cholecystectomies in Hong Kong

open access: yes, 1988
A retrospective study of gallbladders submitted as surgical specimens over a period of fifteen years (1972-1986) was performed in the Department of Pathology, Queen Mary Hospital, Hong Kong.
Chan, KW
core   +1 more source

The multifaceted roles of lysosomes in cancer

open access: yesMolecular Oncology, EarlyView.
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley   +1 more source

Differential Diagnoses in Surgical Pathology: Pancreatic and Biliary Pathology

open access: yes, 2021
New in the Differential Diagnosis in Surgical Pathology series, this abundantly illustrated title helps you systematically solve tough diagnostic challenges in pancreatic and biliary pathology. It uses select images of clinical and pathological findings,
Elizabeth Thompson   +2 more
core  

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

open access: yesMolecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau   +9 more
wiley   +1 more source

The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection

open access: yesMolecular Oncology, EarlyView.
Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński   +12 more
wiley   +1 more source

Vascular normalization confers an endothelial immune suppressive gene expression profile

open access: yesMolecular Oncology, EarlyView.
We compare the immunoregulatory gene expression profiles of healthy endothelial cells or endothelial cells from tumors having a normalized endothelium (low leakage) with that of wild‐type tumors (high leakage) and observe that the wild‐type tumor endothelium exhibits immunostimulatory properties.
Liqun He, Michael Welsh
wiley   +1 more source

The surgical pathology of bilharziasis.

open access: yesSouth African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 2000
Click on the link to view.
openaire   +2 more sources

The UEMS section/board of pathology, chapter 6: requirement for recognition of postgraduate training in pathology: a presentation of the paris document.

open access: yes, 2012
After more than five years discussion the UEMS Section/Board of Pathology agreed a specification of requirements for recognition of post-graduate training in pathology, which is the key to the future of our discipline.
UEMS Section/Board of Pathology meeting in Paris 2012   +7 more
core   +1 more source

Home - About - Disclaimer - Privacy