Results 241 to 250 of about 2,278,162 (304)

Metastatic Pancreatic Adenocarcinoma Downstaged to T0N0 with Chemotherapy and Targeted Therapy, Confirmed by Surgical Pathology: A Case Report. [PDF]

Case Rep Oncol
Ardalan B, Livingstone A, Franceschi D, Sleeman D, Azqueta J, Gonzalez R, England J.   +6 more
europepmc   +1 more source

Critical Coupling in Semi‐Trasparent Fano Resonators for Photothermal Converters

Advanced Functional Materials, EarlyView.
An ultrathin metal–insulator multilayer architecture is engineered to exploit Fano‐resonant critical coupling, completely suppressing optical reflectance while achieving a balanced 50:50 trade‐off between absorbance and transmittance. Upon laser excitation at resonance, the metamaterial generates intense localized heat (ΔT≈550∘C$\Delta T {\approx }550^\
Giuseppe Emanuele Lio, Giuseppe Nicoletta, Roberto Caputo, Antonio Ferraro   +3 more
wiley   +1 more source

Biomimetic Hybrid‐Membrane Nanoreactor for Deep‐Seated Photodynamic Immunotherapy of Hepatocellular Carcinoma via Dual Catalysis‐Enhanced ROS Amplification and cGAS‐STING Activation

Advanced Functional Materials, EarlyView.
UCNP@MnOx‐Hyp@HRM (UMHM) enables tumor targeting and accumulation. Under 808 nm NIR irradiation, PDT/CDT synergistically triggers ICD and cGAS–STING immunity for deep hepatocellular carcinoma therapy. ABSTRACT Photodynamic therapy (PDT) is promising against hepatocellular carcinoma (HCC).
Wen Li, Jianzhang Luo, Pei Lu, Dongqing Liu, Huijun Yi, Xiaoyuan Yi, Bixia Chi, Wen Chen, Qingyu Zeng, Feifei He, Liyan Wang   +10 more
wiley   +1 more source

Biodegradable Conductors for Implantable and Wearable Transient Bioelectronics

Advanced Functional Materials, EarlyView.
Biodegradable conductors are essential building blocks for transient bioelectronics, enabling temporary sensing, stimulation, and energy transfer while eliminating the need for device retrieval. This review summarizes biodegradable metals, conducting polymers, ionic conductors, and conductive composites, highlighting degradation mechanisms, material ...
Yicheng Zhu, Yijun Liu, Naoji Matsuhisa
wiley   +1 more source

Single‐Cell Resolution Mapping of Osteoarthritis‐Associated Chondrocyte Dynamics Using a High‐Density CMOS MEA Platform

Advanced Healthcare Materials, EarlyView.
Single‐cell and spatially resolved impedance mapping using a high‐density CMOS‐MEA platform enables non‐invasive monitoring of osteoarthritis‐associated chondrocyte dynamics. Continuous label‐free measurements reveal heterogeneous remodeling behaviors, including proliferation, migration, and phenotypic transitions, establishing a powerful approach for ...
Neha Deshpande, Pauline Coquart, Bram Theuns, Susanne Cremery, Jaime Rodolfo V. Garcia III, Julien Verplanken, Dennis Lambrechts, Dries Braeken, Liesbet Lagae, Johanna Bolander   +9 more
wiley   +1 more source

Automated Pathologic TN Classification Prediction and Rationale Generation From Lung Cancer Surgical Pathology Reports Using a Large Language Model Fine-Tuned With Chain-of-Thought: Algorithm Development and Validation Study. [PDF]

JMIR Med Inform
Kim S, Jang S, Kim B, Sunwoo L, Kim S, Chung JH, Nam S, Cho H, Lee D, Lee K, Yoo S.   +10 more
europepmc   +1 more source

Self‐Healing Hydrogel‐Enabled Modular Assembly of Bilayered Skin Construct for Hair Follicle Regeneration

Advanced Healthcare Materials, EarlyView.
Self‐healing assembly of two cell‐laden hydrogel layers creates a biomimetic skin construct that restores both dermal and epidermal functions, resulting in accelerated wound healing and enhanced hair follicle regeneration in a full‐thickness skin wound model. ABSTRACT Alopecia remains a pervasive clinical challenge, largely owing to the limited ability
JaeWook Park, Su Yong Kim, MinSu Jeong, Beom Joon Kim, Shin Hyuk Kang, Won‐Gun Koh   +5 more
wiley   +1 more source

Human iPSC‐Derived Tissue‐Engineered Nigrostriatal Pathway for Chronic Restoration of Dopaminergic Axon Tracts in a Rat Parkinson's Model

Advanced Healthcare Materials, EarlyView.
Inspired by conventional cell therapy and emerging bioengineering approaches, the tissue‐engineered nigrostriatal pathway (TE‐NSP) has an anatomically‐inspired design comprising a population of human dopaminergic neurons with unidirectional, long‐projecting axon tracts.
Wisberty J. Gordián‐Vélez, Dimple Chouhan, Kevin D. Browne, James Lim, Saarang P. Karandikar, Rodrigo A. España, John E. Duda, H. Isaac Chen, D. Kacy Cullen   +8 more
wiley   +1 more source

Anti‐Inflammatory and Neuroactive Effects of Polymer‐Coated Iron Oxide Nanoparticles Functionalized With Interleukin 4 for Spinal Cord Injury

Advanced Healthcare Materials, EarlyView.
Polymer‐coated IONPs functionalized with IL‐4 display respective neuroactive and anti‐inflammatory actions on neural progenitor cells and macrophages/microglia in vitro. When examined chronically in a rat experimental model of spinal cord injury, rGO scaffolds carrying these nanosystems adequately integrate into the lesion, significantly reduce ...
Julia Martínez‐Ramírez, Paloma Lozano‐Picazo, María de Lamo‐Atencia, Andrea Ferreras, Esther Benayas‐Martín, Elena Fernández‐López, Marina Sánchez‐Petidier, Verónica Barranco‐Maresca, Víctor Caz, Anne des Rieux, Juliana M. Rosa, María del Puerto Morales, María C. Serrano   +12 more
wiley   +1 more source

Topically Delivered Treg‐Attracting Microparticle‐Hydrogel Composites Recruit Regulatory T Cells and Limit Cardiac Injury After Severe Ischemia

Advanced Healthcare Materials, EarlyView.
CCL22‐releasing PLGA microparticles (MP) suspended in topically applied hydrogels (HEART) establish a sustained chemokine gradient at the injured myocardium. HEART recruits CCR4+ regulatory T cells, reduces infarct size and graft fibrosis, and improves cardiac function.
Matthew A. Borrelli, Alexis T. Reese, Jordan J. P. Warunek, Betsy Ann Varghese, Canxing Lin, Jeffery J. Baust, Brenda McMahon, Steven R. Little, Hēth R. Turnquist   +8 more
wiley   +1 more source