Results 51 to 60 of about 2,278,162 (304)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Biocompatibility of implants in planned and urgent hernia surgery

open access: yesZaporožskij Medicinskij Žurnal, 2021
The aim of the work – to analyze modern scientific and practical achievements in the effectiveness of implants in planned and emergency hernia surgery and to identify promising areas for further research. The literature review presents modern views on
B. I. Slonetskyi   +3 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Implementation of a software application for presurgical case history review of frozen section pathology cases

open access: yesJournal of Pathology Informatics, 2017
Background: The frozen section pathology practice at Mayo Clinic in Rochester performs ~20,000 intraoperative consultations a year (~70–80/weekday). To prepare for intraoperative consultations, surgical pathology fellows and residents review the case ...
Andrew P Norgan   +4 more
doaj   +1 more source

A case of primary renal oncocytic tumor: Chromophobe renal cell carcinoma or oncocytoma?

open access: yesIJU Case Reports, 2023
Introduction “Other oncocytic renal tumors of the kidney” is a new category constituted by 2022 WHO classification and different in the point of morphology and immunohistochemistory from typical oncocytic/eosinophilic renal tumors including chromophobe ...
Kenta Matsui   +5 more
doaj   +1 more source

AgNOR volumes in normal and malignant colorectal and epithelium

open access: yes, 1994
The Annual Meeting of the Hong Kong Division of the International Academy of Pathology, 1993. In International Journal of Surgical Pathology, 1994, v.
Dockery, P, Morais, M, White, FH
core   +1 more source

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

open access: yesFEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda   +2 more
wiley   +1 more source

Reporting Gleason grade/score in synoptic reports of radical prostatectomies

open access: yesJournal of Pathology Informatics, 2016
Context: The format of a synoptic report can significantly affect the accuracy, speed, and preference with which a reader can retrieve information.
Andrew A Renshaw   +2 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

The Role of Artificial Intelligence for Image Analysis in Surgical Pathology [PDF]

open access: yesAnnals of Dunarea de Jos University. Fascicle I : Economics and Applied Informatics, 2020
Nowadays, artificial intelligence (AI) is an important part of our life and it is a field which continues to grow, to develop and to be implemented in many aspects of our daily tasks.
Gabriela Izabela BALTATESCU   +9 more
doaj  

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