Results 101 to 110 of about 1,431,342 (340)

Standardized loads acting in knee implants [PDF]

, 2014
The loads acting in knee joints must be known for improving joint replacement, surgical procedures, physiotherapy, biomechanical computer simulations, and to advise patients with osteoarthritis or fractures about what activities to avoid. Such data would
Bender, Alwina, Bergmann, Georg, Dymke, Joern, Graichen, Friedmar, Heller, Markus O., Kutzner, Ines, Rohlmann, Antonius, Trepczynski, Adam   +7 more
core   +2 more sources

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source

An evaluation of enteral nutrition practices and nutritional provision in children during the entire length of stay in critical care [PDF]

, 2014
<b>Background</b> Provision of optimal nutrition in children in critical care is often challenging. This study evaluated exclusive enteral nutrition (EN) provision practices and explored predictors of energy intake and delay of EN ...
A Slater, AF Rousseau, C Lambe, David Young, DO Health, EJ Rogers, Emma Gentles, GC Briassoulis, GS Doig, GS Doig, H Woien, Hani A Alfheeaid, IM Mitchell, J Hulst, Jackie Mara, JL Vazquez Martinez, JM Hulst, JM Hulst, Konstantinos Gerasimidis, Krystalia Diamantidi, LF Lima, MA Holliday, Mark Davidson, MM Pollack, Neil Spenceley, NM de, R Meyer, RM Taylor, SB de Oliveira Iglesias, T Petrillo-Albarano, TA Mikhailov, TJ Cole, WN Schofield   +32 more
core   +3 more sources

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

Molecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma, Sophia M. Orbach, Kate V. Griffin, Kathryn Kang, Yining Zhang, Rebecca S. Pereles, Ian A. Schrack, Guillermo Escalona, Jacqueline S. Jeruss, Lonnie D. Shea   +9 more
wiley   +1 more source

Robotic-assisted modified retroauricular cervical approach: initial experience in Latin America

Revista do Colégio Brasileiro de Cirurgiões
Objective: to evaluate the thickness of the gastric wall at the time of intra gastric balloon (IGB) placement, at the time of its withdrawal and one month after withdrawal. Methods: fifteen morbidly obese patients underwent the introduction of IGB under
THIAGO CELESTINO CHULAM, RENAN BEZERRA LIRA, LUIZ PAULO KOWALSKI   +2 more
doaj   +1 more source

Could the super-pulsed CO2 laser be used for oral excisional biopsies? [PDF]

, 2019
Background. The main purpose of a biopsy is microscopic examination and diagnosis. Keeping the margins of specimens safe and readable is always fundamental to detecting marginal infiltrations or malignant transformation.
Ambrogiano, Simone, Di Gioia, Cira Rosaria Tiziana, Dominiak, Marzena, Mohsen, Ahmed Amir Mohamed, Palaia, Gaspare, Romeo, Umberto, Tenore, Gianluca   +6 more
core   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Development of a Virtual Laparoscopic Trainer using Accelerometer Augmented Tools to Assess Performance in Surgical training [PDF]

, 2010
Previous research suggests that virtual reality (VR) may supplement conventional training in laparoscopy. It may prove useful in the selection of surgical trainees in terms of their dexterity and spatial awareness skills in the near future.
Child, C. H. T., Doroana, R., Haddad, M., Mohamedally, D., Parkar, S.   +4 more
core  

TRPM8 levels determine tumor vulnerability to channel agonists

Molecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo, Francesco Giuseppe Carbone, Kristi Buzo, Nicole Annesi, Sacha Genovesi, Annalisa Lorenzato, Karen Widmann, Michela Libergoli, Elisa Marmocchi, Giovanni Bertalot, Alberto Brolese, Mauro Giulio Papotti, Luca Molinaro, Orazio Caffo, Mattia Barbareschi, Alberto Bardelli, Alessandro Romanel, Sabrina Arena, Andrea Lunardi   +18 more
wiley   +1 more source

Pharmacologic approaches against advanced glycation end products (ages) in diabetic cardiovascular disease [PDF]

, 2015
Advanced Glycation End-Products (AGEs) are signaling proteins associated to several vascular and neurological complications in diabetic and non-diabetic patients.
Avtaar Singh, Sanjeet Singh, Chello, Massimo, DI DOMENICO, Fabio, Nappi, Francesco, Nenna, Antonio, Spadaccio, Cristiano, Sutherland, Fraser W   +6 more
core   +2 more sources