Results 141 to 150 of about 1,461,330 (339)

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Surgeon Speaks-Paul J. DiMuzio, MD, FACS [PDF]

, 2014
“Patients with extensive acute deep vein thrombosis (DVT) of the legs provide an excellent example of why effective medical-surgical collaboration is so important.

core   +1 more source

Surgical Procedures for Peptic Ulcer: A Critique of the Committee Report

, 1953
K. S. Grimson
openalex   +1 more source

Aortic valvular disease: Pathophysiology and anaesthetic management for general surgical procedures [PDF]

, 1963
Leonard C. Jenkins, W. A. Dodds, H. B. Graves   +2 more
openalex   +1 more source

Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier   +4 more
wiley   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

THE EFFECT OF VARIOUS SURGICAL PROCEDURES UPON THE ACIDITY OF THE GASTRIC CONTENTS OF ULCER PATIENTS*

, 1951
Douglas A. Farmer, Chester W. Howe, William J. Porell, Reginald H. Smithwick   +3 more
openalex   +2 more sources

Some Examples of the Use of Radiography in Equine Surgical Procedures [PDF]

, 1967
E J Roberts
openalex   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Impacto da cirurgia endovascular sobre a cirurgia arterial convencional

Revista do Colégio Brasileiro de Cirurgiões
OBJETIVO: Avaliar o impacto da implantação da cirurgia endovascular (CEV) em um serviço de cirurgia vascular convencional (CVC). MÉTODO: Análise retrospectiva dos procedimentos vasculares nos últimos 11 anos, dos procedimentos arteriais, anuais e por ...
Jó Luis Andrade, Luis Gustavo dos Santos Iniesta Castilho, Bonno van Bellen   +2 more
doaj   +1 more source