Results 141 to 150 of about 3,411,041 (254)

Patients' Preferences for Surgical Procedures in Hidradenitis Suppurativa: A Discrete Choice Experiment. [PDF]

open access: yesPatient
Heinz KC   +8 more
europepmc   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

Minor surgical procedures in primary care in Bahrain: Attitudes, barriers, and implications. [PDF]

open access: yesJ Family Med Prim Care
Almahdi N   +6 more
europepmc   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Fournier's Gangrene in Neonates: A Case Report and Literature Review

open access: yesJournal of Plastic and Reconstructive Surgery
Fournier's gangrene is a severe, rapidly progressing necrotizing fasciitis with a high capacity for compromising tissues at different levels. It primarily affects perianal and genital areas with a high mortality rate due to extensive impact.
Maria Camila González Terán   +2 more
doaj  

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Two hearts beat as one: An easy method to design a hard flap

open access: yesTurkderm Turkish Archives of Dermatology and Venereology, 2021
Leyla Huseynova, Gonca Elçin
doaj   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

Surgical research /

open access: yes, 2001
With the recent changes in the health care industry, surgeons face increasing pressure to devote their time to their clinical activities, thus limiting their research efforts.
Souba, Wiley W.   +1 more
core  

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