Results 41 to 50 of about 2,051,804 (248)

Preventing and treating surgical site infection in patients with spinal metastatic disease [PDF]

, 2013
Surgery to remove secondary spinal tumours is often necessary to relieve symptoms associated with metastatic spinal cord compression (MSCC). However, such individuals are at high risk of surgical site infection (SSI).
Lui, Steve, Atkinson, Ross, Ousey, Karen
core  

Integration of patient-reported outcome measures with key clinical outcomes after immediate latissimus dorsi breast reconstruction and adjuvant treatment

, 2013
Background: linical evidence on patient-reported outcome measures (PROMS) in breast reconstruction is lacking. The aim of this study was to evaluate PROMs in implant-assisted latissimus dorsi (LDI) or tissue-only autologous latissimus dorsi (ALD) flap ...
Haviland, J.S., Betambeau, N., Balta, V., Reece-Smith, A., Benson, J., Winters, Z.E.   +5 more
core   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Reconstructive surgery after distal fibular resection due to bone tumors: a technical report on surgical strategies and results from the PROSPERO international register of systematic reviews

EFORT Open Reviews
Purpose: Primary bone tumors of the fibula are rare. Distal fibular resection has a significant impact on ankle biomechanics and gait, possibly leading to complications such as ankle instability, valgus deformity, and degenerative changes.
Andrea Angelini, Ivan Bohacek, Mihovil Plecko, Carlo Biz, Giulia Trovarelli, Mariachiara Cerchiaro, Giuseppe Di Rubbo, Pietro Ruggieri   +7 more
doaj   +1 more source

Three-dimensional printing of patient-specific surgical plates in head and neck reconstruction: A prospective pilot study [PDF]

, 2018
Background Surgical plates have been extensively used in head and neck reconstruction and conventional plates are mass-produced with universal configurations.
Ruxu Du, Xian-shuai Chen, Wing Shan Choi, Zhang, CY, Du, Ruxu, Leung, Yiu Yan, Justin Paul Curtin, Wei-fa Yang, Yang, Wei-fa, Choi, WS, Curtin, JP, Leung, YY, Su, Yu xiong, Yang, WF, Su, Yu-xiong, Chen, Xian-shuai, Yiu Yan Leung, Yu-xiong Su, Choi, Wing Shan, Chun-yu Zhang, Curtin, Justin Paul, Chen, XS, Zhang, Chun-yu, Su, YX, Du, R   +24 more
core   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Infrainguinal open reconstruction: a review of surgical considerations and expected outcomes

, 2017
Sevan R Komshian, Kimberly Lu, Steven L Pike, Jeffrey J Siracuse Division of Vascular and Endovascular Surgery, School of Medicine, Boston University Boston, MA, USA Abstract: Infrainguinal arterial occlusive disease can lead to ...
Lu K, Kimberly Lu, Steven Pike, Siracuse JJ, Komshian SR, Sevan Komshian, Pike SL, Jeffrey Siracuse   +7 more
core   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Challenges in evaluating surgical innovation [PDF]

, 2009
Research on surgical interventions is associated with several methodological and practical challenges of which few, if any, apply only to surgery. However, surgical evaluation is especially demanding because many of these challenges coincide.
Ergina, Patrick L, Seiler, Christoph M, Boutron, Isabelle, Blazeby, Jane M, Cook, Jonathan Alistair, Clavein, Pierre-Alain, Reeves, Barnaby C   +6 more
core   +2 more sources

Anatomic anterior cruciate ligament reconstruction - aspects of surgical technique [PDF]

, 2016
Anatomic anterior cruciate ligament (ACL) reconstruction is a concept that has gained in interest and it aims to more effectively restore native ACL anatomy and function.
Desai, Neel
core   +1 more source