Results 31 to 40 of about 350,268 (259)

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

A randomized controlled trial comparing large versus small stitch incision closure in gynaecological malignancies (CLaSSIC Study)

Cancer Treatment and Research Communications
Objective: The study aimed to compare Small Stitch Closure (SSC) and Large Stitch Closure (LSC) techniques for reducing incisional ventral hernia (IVH) and surgical site infection (SSI) rates in gynaecological malignancies. Methods: We conducted a single-
Priya Bhati, Monal Garg, Saumya Gupta, Hawwa Hana, Anandita Anandita, Sheejamol V S   +5 more
doaj   +1 more source

Scalpel blade contamination and risk of postoperative surgical site infection following abdominal incisions in dogs

BMC Research Notes, 2019
Objective This prospective observation sought to determine if scalpel blades used for abdominal skin incisions in dogs are a significant source of bacterial contamination, and if these blades should be changed prior to use in deeper dissection.
Christina G. Lioce, Elizabeth C. Davis, Julie W. Bennett, Forrest I. Townsend, Christopher P. Bloch   +4 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Surgical Site Infection

Journal of Islamic International Medical College, 2014
Surgical Site Infection (SSI) accounts for 15% of all nosocomial infections. Post surgical infection leads to higher readmission, increased length of postoperative hospital stay which drastically escalate expenses and jeopardize health outcomes.
Prof. Dr Ishtiaq Ahmed
doaj  

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

The Effect of Duration of Disinfection of Bacterial Flora of Surgical Site

نشریه پرستاری ایران, 2008
Background and Aim: Skin disinfection is an effective method of preventing surgical site infection (SSI), but there is controversy about the duration of skin preparation.
Mitra Zandiyeh, Safar Shams Vala, Sayed Reza Borzo, Fatemeh Masome Ghonoti, Saeid Amiri   +4 more
doaj  

Risk factors associated with surgical site infection after breast surgery [PDF]

Reviews in Clinical Medicine, 2015
Breast surgical site infection is not only one of the main causes of the morbidity and mortality of cases under different types of surgeries, but also it results in longer hospitalization and additional expenses.
Seyed Esmael Nezhadhoseini, Kazem Fotohi, Mohammad Vejdani   +2 more
doaj   +1 more source