Results 61 to 70 of about 5,290 (297)

AI‐Based D‐Amino Acid Substitution for Optimizing Antimicrobial Peptides to Treat Multidrug‐Resistant Bacterial Infection

Advanced Science, EarlyView.
This study constructed the first D‐amino acid antimicrobial peptide dataset and developed an AI model for efficient screening of substitution sites, with 80% of candidate peptides showing enhanced activity. The lead peptide dR2‐1 demonstrated potent antimicrobial activity in vitro and in vivo, high stability, and low toxicity.
Yinuo Zhao, Qingzhou Kong, Haifan Gong, Lixiang Li, Jialu Fu, Boyao Wan, Peizhu Wang, Xiaojuan Li, Yue Wang, Jinghui Zhang, Yanbo Yu, Xiaoyun Yang, Xiuli Zuo, Haina Wang, Yanqing Li   +14 more
wiley   +1 more source

Esofagojejunostomia após gastrectomia total: anastomose mecânica ou manual?

Revista do Colégio Brasileiro de Cirurgiões
OBJETIVO: Os autores apresentam um estudo observacional, transversal, comparando a anastomose manual com a anastomose mecânica para reconstrução do trânsito digestivo em Y de Roux em pacientes submetidos à gastrectomia total para câncer gástrico. MÉTODOS:
Fábio Lopes, André Fonseca dos Reis, Bruno Juste Werneck Côrtes, Dreyfus Silva Fabrini, Henrique Ribeiro Lima, Luiz Carlos Gomes Rocha   +5 more
doaj   +1 more source

Higher‐Level Structural Classification of Pseudomonas Cyclic Lipopeptides through Their Bioactive Conformation

Advanced Science, EarlyView.
Solution structures of a series of cyclic lipodepsipeptides from Pseudomonas reveal that these specialized metabolites adopt left‐handed alpha helical conformations of only two types, being either ‘stapled’ or ‘catch‐pole’ helix. The particular modular distribution of the biosynthetic gene clusters is found to determine the extent of their conserved ...
Benjámin Kovács, Durga Prasad, Vic De Roo, Matthias Vanheede, Penthip Muangkaew, Annemieke Madder, Monica Höfte, René De Mot, Niels Geudens, José C. Martins   +9 more
wiley   +1 more source

Primary colo-anal stapler anastomosis for the surgical treatment of Hirschsprung’s disease in children [PDF]

, 2021
V.P. Prytula, D.Yu. Krivchenya, M. I. Silchenko, O.O. Kurtash, S.F. Hussaini, Ye.O. Rudenko   +5 more
openalex   +1 more source

Catechol Derivative‐Based Bioadhesives: Molecular Design for Precision Medical Adhesion

Advanced Science, EarlyView.
This study utilizes tree‐inspired side‐chain engineering to graft five catechol derivatives onto PVA, systematically revealing how side‐chain length and substituents regulate adhesion and cohesion properties. Among them, the PVA‐CA patch demonstrates superior tissue adhesion, biocompatibility, and promotes regeneration, establishing a programmable ...
Xueyu Wang, Zixin Yang, Shan Wang, Weiwei Tan, Zhirui He, Qinyu Duan, Huanan Wang, Tao Chen, Shanshan Hu   +8 more
wiley   +1 more source

Comparative Effectiveness Assessment of Two Powered Surgical Stapling Platforms in Laparoscopic Sleeve Gastrectomy: A Retrospective Matched Study

Medical Devices: Evidence and Research, 2020
Logan Rawlins,1 Barbara H Johnson,2 Stephen S Johnston,2 Nivesh Elangovanraaj,3 Mohit Bhandari,4 Ricardo V Cohen,5 Karl Peter Rheinwalt,6 Raymond Fryrear,2 Sanjoy Roy2 1Allegheny Health Network Bariatric & Metabolic Institute, Pittsburgh, PA, USA ...
Rawlins L, Johnson BH, Johnston SS, Elangovanraaj N, Bhandari M, Cohen RV, Rheinwalt KP, Fryrear R, Roy S   +8 more
doaj  

Beyond the Ban—Shedding Light on Smallholders' Price Vulnerability in Indonesia's Palm Oil Industry

Applied Economic Perspectives and Policy, EarlyView.
ABSTRACT The Indonesian government imposed a palm oil export ban in April 2022 to address rising cooking oil prices. This study explores oil palm smallholders' vulnerability to the policy using descriptive statistics, Lasso, and post‐Lasso OLS regressions.
Charlotte‐Elena Reich, Tim Ölkers, Vanessa Bonke, Oliver Musshoff   +3 more
wiley   +1 more source

Feasibility of Uniportal Thoracoscopic Right Medial-Basal (S7) Segmentectomy

Annals of Thoracic Surgery Short Reports
Thoracoscopic right medial-basal (S7) segmentectomy is technically challenging due to its small size, depth, and anatomical complexity, especially through a uniportal thoracoscopic approach because of the limited angulation of the surgical instruments or
Hitoshi Igai, MD, PhD, Akinobu Ida, MD, Kazuki Numajiri, MD, Kazuhito Nii, MD, PhD, Mitsuhiro Kamiyoshihara, MD, PhD   +4 more
doaj   +1 more source

Climate Change Agricultural Comparative Advantage and the US Trade Balance

Applied Economic Perspectives and Policy, EarlyView.
ABSTRACT Current science indicates that warming and elevated atmospheric CO2 will have ambiguous results for crop productivity depending on crop type and geographic location, whereas increased heat stress makes livestock and human labor less productive.
Elizabeth A. Fraysse, Thomas W. Hertel, Roman Keeney   +2 more
wiley   +1 more source

The impact of the Russia–Ukraine war on stock prices, profits and perceptions in the food supply chain

Agribusiness, EarlyView.
Abstract The Russian invasion of Ukraine in February 2022 had profound consequences for the global economy. As both countries are major commodity exporters, the food value chain was also affected. This study investigates the impact of the invasion on stock prices, profitability and sentiments of agribusinesses along the food supply chain by using an ...
Julia Höhler, Ivo Harmens, Alfons Oude Lansink   +2 more
wiley   +1 more source