Results 31 to 40 of about 18,664,498 (235)

Evaluation of the Ballyfermot Strengthening Families Programme [PDF]

, 2010
The Strengthening Families Programme (SFP) is an internationally recognised parenting and family skills initiative for high-risk families. It was developed by Dr.
Strengthening Families Programme
core  

Issues of Organization of the Cardiac Surgical Care in Ukraine under Martial Law

Український журнал серцево-судинної хірургії, 2023
The aim. To study and substantiate the new principles of organization in the provision of cardiac surgical care under martial law. Materials and methods.
Mykola L. Rudenko, Olha M. Unitska, Andrii G. Goriachev, Tetiana A. Andrushchenko, Nataliia M. Verych   +4 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Estimating access to surgical care: A community centered national household survey from Pakistan.

PLOS Global Public Health, 2023
Pakistan is a lower middle-income country in South Asia with a population of 225 million. No estimate for surgical care access exists for the country. We postulate the estimated access to surgical care is less than the minimum 80% to be achieved by 2030.
Muhammad Nabeel Ashraf, Irum Fatima, Ammar Ali Muhammad, Katherine Albutt, Manon Pigeolet, Asad Latif, John G Meara, Lubna Samad   +7 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Scalable policy adoption and sustainable implementation of surgical care in the Americas

Revista Panamericana de Salud Pública
On September 29, 2023, the Republic of Ecuador convened a meeting to address surgical system strengthening and urge political leaders to invest in surgical infrastructure.
Nikathan Kumar, Gabriella Y. Hyman, Ayla Gerk, Taylor Wurdeman, Tarsicio Uribe-Leitz, Scott Corlew, Kee B. Park, John G. Meara, Robert Riviello, Emmanuel M. Makasa, Jimmy Kolker, Joanne Manrique, Rubén E. Ayala, Geoffrey C. Ibbotson, Alex Mejia, Luiz Fernando Falcão, Maria Jose Garcia Fuentes, Mauricio Montalvo-Samaniego, Ivonne A. Baki, Ernesto Bascolo, Alfredo Borrero Vega   +20 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Globalization of national surgical, obstetric and anesthesia plans: the critical link between health policy and action in global surgery

Globalization and Health, 2020
Efforts from the developed world to improve surgical, anesthesia and obstetric care in low- and middle-income countries have evolved from a primarily volunteer mission trip model to a sustainable health system strengthening approach as private and public
Paul Truché, Haitham Shoman, Ché L. Reddy, Desmond T. Jumbam, Joanna Ashby, Adelina Mazhiqi, Taylor Wurdeman, Emmanuel A. Ameh, Martin Smith, Edwin Lugazia, Emmanuel Makasa, Kee B. Park, John G. Meara   +12 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Establishing a baseline for surgical care in Mongolia: a situational analysis using the six indicators from the Lancet Commission on Global Surgery

BMJ Open, 2022
Objectives To inform national planning, six indicators posed by the Lancet Commission on Global Surgery were collected for the Mongolian surgical system.
Raymond R Price, Ali Jalali, Anudari Zorigtbaatar, Sarnai Erdene, Sergelen Orgoi, Andrea Davis, Jonathan Nellermoe, Jade M Nunez, Simon Ruhnke, Battsetseg Gonchigjav, Nomindari Bat-Erdene, Kevin Bagley, Micah Katz, Hannah Pioli, Batsaikhan Bat-Erdene, Ganbold Lundeg   +15 more
doaj   +1 more source