Results 91 to 100 of about 17,004,467 (250)
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
An efficient decomposition approach for surgical planning [PDF]
, 2012 This talk presents an efficient decomposition approach to surgical planning. Given a set of surgical waiting lists (one for each discipline) and an operating theater, the problem is to decide the room-to-discipline assignment for the next planning period
A. Coppi +11 more
core
The psychological impact of surgical complications on patients and surgeons [PDF]
, 2013 Adverse events constitute a significant challenge for healthcare organisations not only in terms of their prevention but also in terms of their after-effects on the injured patients and the staff involved.
Pinto, Anna
core +1 more source
Clinical and Experimental Dental ResearchObjectives The relationship between tinnitus and temporomandibular disorders (TMD) over the years has continued to be widely debated in literature and not yet fully understood.
Henri Albert Didier +13 more
doaj +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
TEMPORAL EVOLUTION AND CONTEXTUAL FACTORS OF SURGICAL SITE INFECTION RATES IN A TERTIARY HOSPITAL
Brazilian Journal of Infectious DiseasesIntroduction/Objectives: Surgical Site Infections (SSIs) represent one of the main causes of morbidity and mortality among Healthcare-Associated Infections (HAIs), accounting for about 20% of HAIs, prolonging hospital stays, negatively impacting patient ...
Lafaiete Barboza da Cruz +4 more
doaj +1 more source
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
FEBS Letters, EarlyView.Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Frimand Needle Holder Reduces Suturing Time and Surgical Stress When Suturing in Palm Grip
, 2016 The Frimand needle holder (FNH) was developed to facilitate palm grip suturing. In the present study, we wanted to examine the impact of the FNH compared with a conventional Hegar-styled needle holder (HSNH) on suture time and surgical ...
Thorlacius, Henrik, +3 more
core +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source