Results 1 to 10 of about 535,677 (366)
Surgical Wound Morbidity in an Austere Surgical Environments [PDF]
Military Medicine, 2000 Surgical wound morbidity was analyzed for a U.S. military field hospital deployed to the Republic of Haiti in support of Operation New Horizons 1998. The purpose of the analysis was to determine whether procedures performed in the field hospital had greater infectious risks as a result of the environment compared with historical reports for traditional
Paul A. Lucha +7 more
openalex +6 more sources
Debridement for surgical wounds [PDF]
Cochrane Database of Systematic Reviews, 2008 Surgical wounds that become infected are often debrided because clinicians believe that removal of this necrotic or infected tissue will expedite wound healing. There are numerous methods available but no consensus on which one is most effective for surgical wounds.To determine the effect of different methods of debridement on the rate of debridement ...
Smith, Fiona +3 more
openaire +8 more sources
Journal of Orthopaedic Surgery and Research, 2022 Background Treatment of open fractures remains a significant challenge in trauma care as these fractures are accompanied by extensive soft tissue damage, exposing the wound site to contaminants and increasing infection risk.
Michael E. Whitely +5 more
doaj +1 more source
FK506 increases susceptibility to musculoskeletal infection in a rodent model
BMC Musculoskeletal Disorders, 2022 Background Delayed fracture healing caused by soft tissue loss can be resolved by the administration of a Th1 immunosuppressant, such as FK506. Additionally, open fractures are at high risk for infection.
Stefanie M. Shiels +2 more
doaj +1 more source
Effect of valproic acid upon skeletal muscle subjected to prolonged tourniquet application
Trauma Surgery & Acute Care Open, 2023 Background Valproic acid (VPA), a histone deacetylase inhibitor, has shown improved outcomes when used as a pharmaceutical intervention in animal studies of hemorrhage, septic shock, and combined injuries.
Robert Moritz +4 more
doaj +1 more source
Journal of Experimental Orthopaedics, 2022 Purpose Delayed fracture healing is a common consequence of polytrauma (PT) occurring in patients with multiple injuries. We believe that when early release of high mobility group box 1 (HMGB1) molecules from necrotic tissues exceed their normal levels ...
Preeti J. Muire +3 more
doaj +1 more source
Journal of Experimental Orthopaedics, 2023 Purpose The mitochondrial DNA (mtDNA) activated cyclic guanosine monophosphate–adenosine monophosphate synthase—stimulator of interferon genes (cGAS‐STING) signaling pathway is a key player in mediating immune responses in autoimmune disorders and cancer.
Preeti J. Muire +3 more
doaj +1 more source
Changes in the length and area of congenital nevi involving the face and extremities after two serial excisions [PDF]
Archives of Aesthetic Plastic Surgery, 2021 Background The objective of this study was to determine the outcome of serial excisions of congenital nevi involving the face and extremities and to calculate changes in the area and length of the nevi.
Jae Il Choi, Daegu Son
doaj +1 more source
A Soft Skin Adhesive (SSA) Patch for Extended Release of Pirfenidone in Burn Wounds
Pharmaceutics, 2023 As much as half or more of deep partial-thickness burn wounds develop hypertrophic scarring and contracture. Once formed, treatments are only minimally effective.
Eugene P. Chung +10 more
doaj +1 more source
Scientific Reports, 2021 In burn patients Pseudomonas aeruginosa infection is a major cause of morbidity. Analysis of the pathogen’s gene expression as it transitions from colonization to acute and then biofilm wound infection may provide strategies for infection control. Toward
Peter D’Arpa +3 more
doaj +1 more source