Results 11 to 20 of about 3,047,253 (407)

Probiotics and Their Effect on Surgical Wound Healing: A Systematic Review and New Insights into the Role of Nanotechnology

open access: yesNutrients, 2021
Skin tissue repair is of fundamental importance for maintaining homeostasis regulation, protection barrier, absorption, and excretion of skin tissue.
A. Bekiaridou   +4 more
semanticscholar   +1 more source

Effect of valproic acid upon skeletal muscle subjected to prolonged tourniquet application

open access: yesTrauma Surgery & Acute Care Open, 2023
Background Valproic acid (VPA), a histone deacetylase inhibitor, has shown improved outcomes when used as a pharmaceutical intervention in animal studies of hemorrhage, septic shock, and combined injuries.
Robert Moritz   +4 more
doaj   +1 more source

Forearm reconstruction with acellular dermal matrix after giant plexiform neurofibroma excision: case reports [PDF]

open access: yesRevista Brasileira de Cirurgia Plástica, 2022
Introduction: Giant plexiform neurinoma is a neuroectoderm and inherited disease. It is an uncommon skin tumor associated with NF1, characterized as a benign peripheral nerve sheath tumor surrounding multiple nervous fascicles.
Eduardo Madalosso Zanin   +7 more
doaj   +1 more source

Preclinical evaluation of a commercially available biofilm disrupting wound lavage for musculoskeletal trauma

open access: yesJournal of Orthopaedic Surgery and Research, 2022
Background Treatment of open fractures remains a significant challenge in trauma care as these fractures are accompanied by extensive soft tissue damage, exposing the wound site to contaminants and increasing infection risk.
Michael E. Whitely   +5 more
doaj   +1 more source

FK506 increases susceptibility to musculoskeletal infection in a rodent model

open access: yesBMC Musculoskeletal Disorders, 2022
Background Delayed fracture healing caused by soft tissue loss can be resolved by the administration of a Th1 immunosuppressant, such as FK506. Additionally, open fractures are at high risk for infection.
Stefanie M. Shiels   +2 more
doaj   +1 more source

Neutralization of HMGB1 improves fracture healing and γδ T lymphocyte counts at the fracture site in a polytrauma rat model

open access: yesJournal of Experimental Orthopaedics, 2022
Purpose Delayed fracture healing is a common consequence of polytrauma (PT) occurring in patients with multiple injuries. We believe that when early release of high mobility group box 1 (HMGB1) molecules from necrotic tissues exceed their normal levels ...
Preeti J. Muire   +3 more
doaj   +1 more source

Multi-modal Wound Classification using Wound Image and Location by Deep Neural Network [PDF]

open access: yesSci Rep 12, 20057 (2022), 2021
Wound classification is an essential step of wound diagnosis. An efficient classifier can assist wound specialists in classifying wound types with less financial and time costs and help them decide an optimal treatment procedure. This study developed a deep neural network-based multi-modal classifier using wound images and their corresponding locations
arxiv   +1 more source

Fracture healing in a polytrauma rat model is influenced by mtDNA:cGAS complex mediated pro‐inflammation

open access: yesJournal of Experimental Orthopaedics, 2023
Purpose The mitochondrial DNA (mtDNA) activated cyclic guanosine monophosphate–adenosine monophosphate synthase—stimulator of interferon genes (cGAS‐STING) signaling pathway is a key player in mediating immune responses in autoimmune disorders and cancer.
Preeti J. Muire   +3 more
doaj   +1 more source

Changes in the length and area of congenital nevi involving the face and extremities after two serial excisions [PDF]

open access: yesArchives of Aesthetic Plastic Surgery, 2021
Background The objective of this study was to determine the outcome of serial excisions of congenital nevi involving the face and extremities and to calculate changes in the area and length of the nevi.
Jae Il Choi, Daegu Son
doaj   +1 more source

A Soft Skin Adhesive (SSA) Patch for Extended Release of Pirfenidone in Burn Wounds

open access: yesPharmaceutics, 2023
As much as half or more of deep partial-thickness burn wounds develop hypertrophic scarring and contracture. Once formed, treatments are only minimally effective.
Eugene P. Chung   +10 more
doaj   +1 more source

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