Results 41 to 50 of about 535,677 (366)

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

Exploring quality of life, physical and psychosocial morbidity for patients with non-infected wounds: a pilot study [PDF]

, 2014
This article reports on the results of a pilot study exploring health-related quality of life and the experience of being resilient in patients who develop acute, non-infected surgical wounds.
Edward, Karen-Leigh, Ousey, Karen, Stephenson, John   +2 more
core  

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

FEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile, Daniela Ratto, Giorgia Rastelli, Ottavia Eleonora Ferraro, Caterina Temporini, Sunil Kumar, Simona Boncompagni, Paola Rossi, Monica Canepari   +8 more
wiley   +1 more source

Observational Analysis of Point-of-Care Lactate Plus™ Meter in Preclinical Trauma Models

Diagnostics
Background/Objectives: Blood lactate concentration is often used to assess systemic hypoperfusion, tissue hypoxia, and sepsis in trauma patients and serves as a prognostic indicator and marker of response to therapy.
Catharina Gaeth, Jamila Duarte, Alvaro Rodriguez, Amber Powers, Randolph Stone   +4 more
doaj   +1 more source

Surgical Wound Dehiscence Treatment

Indonesian Journal of Obstetrics and Gynecology, 2023
Objective: This article describes management of surgical wound dehiscence. in a cesarean section. Method: Case report. Case: A 39 years-old woman, P4, presented with reddish pus coming out from open surgical wound on day 4 following a caesarean section ...
Riyan H. Kurniawan, Ni Putu C. D. Atmantika, Achmad K. Harzif, Dewita Nilasari   +3 more
doaj   +1 more source

Dialkylcarbamoyl chloride (DACC)-coated dressings in the management and prevention of wound infection: A systematic review [PDF]

, 2017
Objective: Dialkylcarbomoyl chloride (DACC)-coated dressings (Leukomed Sorbact and Cutimed Sorbact) irreversibly bind bacteria at the wound surface that are then removed when the dressing is changed.
Bua, N., Carradice, D., Chetter, I.C., Harwood, A.E., Smith, G.E., Totty, J.P., Wallace, T.   +6 more
core   +1 more source

Wound implantation—a surgical hazard [PDF]

Journal of British Surgery, 1977
Abstract A review of the literature on wound implantation together with a report on an unusual case of implantation of squamous carcinoma at the site of a gastrostomy is presented.
G. B. Ong, T T Alagaratnam
openaire   +2 more sources

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

FEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona, Carlo M. Bergamini, Carlo Ferrari, Stefano Volinia, Nicoletta Bianchi   +4 more
wiley   +1 more source

Comparison of Intact Fish Skin Graft and Allograft as Temporary Coverage for Full-Thickness Burns: A Non-Inferiority Study

Biomedicines
The extent and depth of burn injury may mandate temporary use of cadaver skin (allograft) to protect the wound and allow the formation of granulation tissue while split-thickness skin grafts (STSGs) are serially harvested from the same donor areas ...
Randolph Stone, Emily C. Saathoff, David A. Larson, John T. Wall, Nathan A. Wienandt, Skuli Magnusson, Hilmar Kjartansson, Robert J. Christy, Shanmugasundaram Natesan   +8 more
doaj   +1 more source

Exploring resilience for people with type 2 diabetes who have a wound [PDF]

, 2015
Comorbidities related to diabetes such as chronic wounds can increase the need for surgical procedures, with at least 10% of all patients undergoing surgery having diabetes.
Edward, Karen-Leigh, Ousey, Karen
core