Results 231 to 240 of about 3,103,046 (298)

Enterobacter-Related Deep Sternal Wound Infection After Cardiac Surgery with Delayed Negative-Pressure Wound Therapy Success: A Case Report. [PDF]

Int Med Case Rep J
Al Ayoubi O, Aldakak MA, Tannous G, Senjab A, Al-Dairy A.   +4 more
europepmc   +1 more source

Intrasplenic Thymus Organogenesis from Injectable Tissue Fragments Restores Functional T‐Cell Immunity

Advanced Science, EarlyView.
Clinical intramuscular thymus transplantation yields only short‐lived efficacy and marginal therapeutic benefits. Benefiting from the spleen's intrinsic strengths—rapid vascular perfusion, abundant developmental factors, and resident progenitors—the intrasplenic thymic grafts achieve robust thymic regeneration and substantial T‐cell reconstitution ...
Shaocong Wang, Zijian Zhang, Fulin Dai, Zhijie Yin, Zhen Xing, Yurong Li, Haochong Lei, Junfeng Zhang, Chunyan Liu, Yan Li, Lei Dong   +10 more
wiley   +1 more source

Incidence and Determinants of Surgical Site Infections in Upper Limb Surgeries: A Multicentric retrospective cohort Study from Tertiary Referral Hospitals in Jordan. [PDF]

Orthop Rev (Pavia)
Akel A, Daseh A, Bin Tareef E, Al-Shamaileh Y, Al-Halasa F, Abuqudiri AZ, Halawani W, Abu-Nar A, Abu-Nawwas MK, Al-Saqqa ES, Abu-Hazeem A, Abu-Jeyyab M.   +11 more
europepmc   +1 more source

Targeting the NR1D1–IGF2BP2–V‐ATPase Axis With Hybrid Nanovesicles Restores Macrophage Rhythms to Reverse Sepsis‐Induced Immunosuppression

Advanced Science, EarlyView.
Sepsis disrupts immune‐cell rhythms and weakens bacterial clearance. Biomimetic nanovesicles combining erythrocyte and inflammation‐activated macrophage membranes deliver siNR1D1 to dysfunctional macrophages, restoring the NR1D1–IGF2BP2–V‐ATPase pathway, circadian regulation, phagolysosomal acidification, and antimicrobial defense.
Lang Chen, Wenyi Lin, Lang Jiang, Xuehui Gao, Chenyan Yu, Jili Han, Zhenping Liu, Xuefeng Li, Mei He, Chang Li, Qilan Li, Chaoying Song, Jiqian Xu, You Shang   +13 more
wiley   +1 more source

Susceptibility-guided use of gentamicin-loaded calcium sulfate after surgical debridement for complex diabetes-related foot infection: a single-centre case series. [PDF]

Front Surg
Cetinkaya OA, Tuzken I, Demirkan A, Boztug CY, Uncu H.   +4 more
europepmc   +1 more source

KLF5 Downregulation Links Impaired BNIP3‐Mediated Mitophagy to Inflammatory Valve Remodeling in Calcific Aortic Valve Disease

Advanced Science, EarlyView.
In human CAVD, KLF5 is reduced in VIC‐rich regions and remodeling/stress‐associated VIC states. In VICs, KLF5 sustains BNIP3 promoter activity and BNIP3‐mediated mitophagy, thereby limiting cytosolic mtDNA accumulation. KLF5 loss weakens mitochondrial quality control and enhances mtDNA‐sensitive STING/NF‐κB/NLRP3 inflammatory signaling under osteogenic
Jin‐Hui Bian, Jia‐Xi Gu, Zhang Yue, Chun‐Ze Yuan, Hai‐Bin Ji, Ao Li, Yu Zhong, Xiu‐Fan Xu, Yu‐Qiu He, Ye‐Fan Jiang, Hong‐Shan Chen, Xiang Chen, Meng‐Lin Chao, Yong‐Feng Shao   +13 more
wiley   +1 more source

Wound problems and infections after major joint arthroplasty : national survey results from primary and secondary care in the UK. [PDF]

Bone Jt Open
Lamb JN, Petheram TG, Lenguerrand E, Whitehouse MR, Moore AJ.   +4 more
europepmc   +1 more source

SerpinA3 is an Endogenous TGF‐β Receptor Antagonist that Attenuates Cardiac Fibroblast Activation and Fibrotic Remodeling

Advanced Science, EarlyView.
SerpinA3 acts as an endogenous TGF‐β receptor antagonist that binds to the extracellular domain of TGFR‐1, thereby preventing TGFR‐1–TGFR‐2 complex formation. This receptor‐level blockade suppresses TGF‐β/Smad2/3 signaling, attenuates cardiac fibroblast activation, and extracellular matrix deposition, and ultimately alleviates pressure overload–induced
Hui Wang, Jieyu Cui, Chunlu Huang, Wanyi Guo, Tong Liu, Yi Zhu, Shuai Shao, Kangyin Chen, Jinlong He, Qiankun Bao   +9 more
wiley   +1 more source

Navigating Treatment Pathways in Diabetic Foot Infection: A Practical Retrospective Analysis of Healing Predictors and the WIfI System. [PDF]

Int Wound J
Tabashiri A, Ghodratnia F, Sam Daliri P, Farahani A, Niazi SG, Rezaee H, Alavi Darazam I.   +6 more
europepmc   +1 more source

Necrotizing abdominal wall infection along a prior drain pathway: A case report and literature review. [PDF]

Radiol Case Rep
Leary RHO, Kleiner D.
europepmc   +1 more source