Results 51 to 60 of about 27,994 (237)

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

EVALUATING PRIVATELY FUNDED PUBLIC RESEARCH: AN EXAMPLE WITH POULTRY AND EGGS [PDF]

A procedure is described for evaluating poultry and egg research projects. A peer review questionnaire and benefit-cost analysis are utilized incorporating elasticities from an econometric model for poultry and eggs.
Martinez, Stephen W., Norton, George W.
core   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Environmental efficiency of small farms in selected EU NMS [PDF]

The objective of this paper is to investigate the relationship between the environmental efficiency and farm commercialisation in selected EU NMS (Bulgaria, Romania and Poland).
Suta, Cornelia Madalina, Davidova, Sophia, Bailey, Alastair   +2 more
core   +1 more source

The Corn Model, Gluts and Surplus Value. [PDF]

, 2006
The controversy over Ricardo's corn model has focused on the interpretation of his early writings. Here, Ricardo's later use of a corn model example in his dispute with Malthus over gluts is discussed.
Glyn, Andrew
core   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Growth, Distribution, Stability and Government Budget Surplus: The Extended Cambridge Equation Revisited [PDF]

In the late 80’s Pasinetti showed that the essential feature of the Cambridge Equation is preserved in his model of growth and income distribution with balanced or unbalanced budget.
Joanílio Rodolpho Teixeira
core  

The Corn Model, Gluts and Surplus Value. [PDF]

, 2004
The controversy over Ricardo’s corn model has focussed on the interpretation of his early writings. Here Ricardo’s later use of a corn model example in his dispute with Malthus over gluts is discussed.
Glyn, Andrew
core   +1 more source

The corn model, gluts and surplus value [PDF]

The controversy over Ricardo's corn model has focused on the interpretation of his early writings. Here, Ricardo's later use of a corn model example in his dispute with Malthus over gluts is discussed.
Andrew Glyn
core   +1 more source