Results 201 to 210 of about 364,351 (266)

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

CT-based vascular invasion in pancreatic ductal adenocarcinoma compared with intraoperative and histological findings. [PDF]

Insights Imaging
Nacul Mora G, Andreou A, Maksoud Z, Becker F, Heitplatz B, Wardelmann E, Strücker B, Katou S, Morgül H, Pascher A, Köhler M, Pöhler GH.   +11 more
europepmc   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Motherhood, the "blank slate," and the language of surrogacy. [PDF]

Front Glob Womens Health
Gribble KD.
europepmc   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Mechanical validation of 3D-printed orthopaedic surrogate models for screw insertion training. [PDF]

Eur J Orthop Surg Traumatol
Thomassen A, Lee B, Granger M, Massey P, Chauvin B, Addevico F, Solitro G.   +6 more
europepmc   +1 more source

Differential Diagnosis of Parotid Tumors on Ultrasound: Interobserver Variability and Examiner-Specific Decision Rules-A Machine Learning Approach. [PDF]

Diagnostics (Basel)
Pillong L, Ohnesorg I, Brust LA, Palm J, Schulze-Berge J, Bozzato V, Voges M, Müller A, Garner M, Bozzato A.   +9 more
europepmc   +1 more source

High-Temperature Mechanical Characterization of CeO₂ as a Ceramic Surrogate Fuel Based on FIB and Nanoindentation. [PDF]

Materials (Basel)
Si J, Xu J, He S, Xie D, Dong C, Zhu P, Qiu R.   +6 more
europepmc   +1 more source

Reliability-based mix design for concrete compressive strength using a physics-prior residual-learning surrogate with calibrated uncertainty. [PDF]

PLoS One
Qu P, Song L, Wang S.
europepmc   +1 more source

Supporting Informed Surrogate Decision-Making in Deceased Donor Intervention Research: Co-Creating Educational Materials With Families. [PDF]

Crit Care Explor
Murphy N, Weijer C, Beitel J, Donaghy M, French N, Goddard C, Gross JA, Slessarev M.   +7 more
europepmc   +1 more source