Results 291 to 300 of about 24,324,331 (382)

Estimating future temperature maxima in lakes across the United States using a surrogate modeling approach. [PDF]

PLoS One, 2017
Butcher JB, Zi T, Schmidt M, Johnson TE, Nover DM, Clark CM.   +5 more
europepmc   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Surrogate modeling of deformable joint contact using artificial neural networks. [PDF]

Med Eng Phys, 2015
Eskinazi I, Fregly BJ.
europepmc   +1 more source

Sensitivity analysis and surrogate modeling of a sulfur-driven autotrophic denitrification model

Andrea Trucchia, Grazia Guerriero, Alberto Tenore, Fabiana Russo, Maria Rosaria Mattei, Luigi Frunzo   +5 more
openalex   +1 more source

Surrogate modeling of microwave circuits using polynomial functional interpolants

, 2010
José E. Rayas‐Sánchez, Jorge Aguilar‐Torrentera, Jorge A. Jasso-Urzua   +2 more
openalex   +2 more sources

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Development of a Predictive Modeling System for Validation of the Cumulative Mirobial Inactivation of the Salmonellae in Pepperoni Utilizing a Non-Pathogenic Surrogate Microorganism (Enterococcus faecalis)

, 2013
Scott Donald Stillwell
openalex   +1 more source

Wind Farm Power Prediction Using a Machine Learning Surrogate Model from a First-Principles Simulation Model

Sebastian Pralong, Samuel Martínez-Gutiérrez, Dan E. Kröhling, Alejandro Merino, Gonzalo E. Álvarez, Daniel Sarabia, Ernesto Martínez   +6 more
openalex   +1 more source