Results 51 to 60 of about 223,298 (311)
ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye +33 more
wiley +1 more source
The enhanced multi-objective symbolic discretization for time series (eMODiTS) method employs a flexible discretization scheme using different value cuts for each non-equal time interval, which incurs a high computational cost for evaluating each ...
Aldo Márquez-Grajales +3 more
doaj +1 more source
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola +4 more
wiley +1 more source
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
Approximated models for aerodynamic coefficients estimation in a multidisciplinary design environment [PDF]
In this paper variable fidelity analyses are investigated. Moreover different kind of approximations to be used in a wide multidisciplinary design environment for aircraft design are built.
Tosetti, Marco +2 more
core
Surrogate Models for Optimization of Dynamical Systems
Khowaja K, Shcherbatyy M, Karl Härdle W. Surrogate Models for Optimization of Dynamical Systems. In: Belomestny D, Butucea C, Mammen E, Moulines E, Reiß M, Ulyanov VV, eds. Foundations of Modern Statistics.
Shcherbatyy, Mykhaylo +8 more
core +1 more source
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Hierarchical surrogate modeling for illumination algorithms [PDF]
Evolutionary illumination is a recent technique that allows producing many diverse, optimal solutions in a map of manually defined features. To support the large amount of objective function evaluations, surrogate model assistance was recently introduced.
openaire +2 more sources
Computational models of electrochemical biodegradation of magnesium (Mg)‐based implants are uncertain. To quantify the model uncertainty, iterative evaluations are needed.
Tamadur AlBaraghtheh +2 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source

