Results 51 to 60 of about 223,298 (311)

Therapeutic Apheresis in Nigeria: A Multi‐Center Summary of Abstracts From the Inaugural Nigerian Society for Apheresis Scientific Meeting

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye   +33 more
wiley   +1 more source

Surrogate-Assisted Symbolic Time-Series Discretization Using Multi-Breakpoints and a Multi-Objective Evolutionary Algorithm

open access: yesMathematical and Computational Applications
The enhanced multi-objective symbolic discretization for time series (eMODiTS) method employs a flexible discretization scheme using different value cuts for each non-equal time interval, which incurs a high computational cost for evaluating each ...
Aldo Márquez-Grajales   +3 more
doaj   +1 more source

Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola   +4 more
wiley   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo   +5 more
wiley   +1 more source

Approximated models for aerodynamic coefficients estimation in a multidisciplinary design environment [PDF]

open access: yes, 2011
In this paper variable fidelity analyses are investigated. Moreover different kind of approximations to be used in a wide multidisciplinary design environment for aircraft design are built.
Tosetti, Marco   +2 more
core  

Surrogate Models for Optimization of Dynamical Systems

open access: yes, 2023
Khowaja K, Shcherbatyy M, Karl Härdle W. Surrogate Models for Optimization of Dynamical Systems. In: Belomestny D, Butucea C, Mammen E, Moulines E, Reiß M, Ulyanov VV, eds. Foundations of Modern Statistics.
Shcherbatyy, Mykhaylo   +8 more
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Hierarchical surrogate modeling for illumination algorithms [PDF]

open access: yesProceedings of the Genetic and Evolutionary Computation Conference Companion, 2017
Evolutionary illumination is a recent technique that allows producing many diverse, optimal solutions in a map of manually defined features. To support the large amount of objective function evaluations, surrogate model assistance was recently introduced.
openaire   +2 more sources

Best Practices in Developing a Workflow for Uncertainty Quantification for Modeling the Biodegradation of Mg‐Based Implants

open access: yesAdvanced Science
Computational models of electrochemical biodegradation of magnesium (Mg)‐based implants are uncertain. To quantify the model uncertainty, iterative evaluations are needed.
Tamadur AlBaraghtheh   +2 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

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