Plasma and breast milk pharmacokinetics of suvorexant in healthy lactating women
Aim This paper aims to evaluate the plasma and breast milk pharmacokinetics of suvorexant, an orexin receptor antagonist used to treat insomnia at a maximum dose of 20 mg, in healthy lactating women. Methods The paper reports on an open‐label Phase 1 study in 12 healthy lactating women.
Jacqueline McCrea +10 more
wiley +1 more source
Electroconvulsive Therapy Refusal in Severe Psychosis: Navigating Capacity, Surrogate Decision-Making, and Ethical Duty. [PDF]
Perera K +4 more
europepmc +1 more source
Improvement in medication adherence is often proposed as a potential advantage of pharmacogenetic‐guided prescribing over a traditional one‐size‐fits‐all approach. This paper provides a review of the published literature and presents the findings of studies that measure adherence to medication as an outcome of pharmacogenetic‐informed care, or that ...
Lucy Galloway +2 more
wiley +1 more source
What might Confucius say? Digital doppelgängers for people who are newly dead, dying, or comatose. [PDF]
Jecker NS, Nie JB, Ho A.
europepmc +1 more source
Ceftriaxone‐associated immune haemolytic anaemia: A patient‐level systematic review
Abstract Ceftriaxone can cause acute haemolysis. Its clinical presentation, risk factors, and outcomes remain incompletely characterized. We conducted a systematic review of published cases with patient‐level data, following international guidelines and with registration in PROSPERO (CRD420261338709). Reports were identified through three bibliographic
Sonja Miotti +9 more
wiley +1 more source
Spiritual counselling and women's well-being in orthodox christianity: embryo adoption as surrogate motherhood. [PDF]
Tarabrin R.
europepmc +1 more source
The global extent of polypharmacy in neonatal intensive care: A systematic review
Aims Pharmaceutical treatment in the neonatal intensive care unit (NICU) is challenging, with neonates often receiving multiple drugs during hospitalization. Given their physiological immaturity, polypharmacy raises concerns about potential adverse effects, drug–drug interactions and the risk of supratherapeutic or subtherapeutic treatment.
Mia Finserås Bretun +6 more
wiley +1 more source
Dynamic Succession of the Early-Life Gut Microbiota and the Regulatory Role of Human Milk Oligosaccharides. [PDF]
Yin J, Wang Z, Ding Y.
europepmc +1 more source
Ghost mothers: Ethical challenges in Iran as an emerging destination for cross-border surrogacy: A case report. [PDF]
Modabber M +4 more
europepmc +1 more source
Abstract In early childhood education many researchers and professionals across the world have embraced the United Nations Convention on the Rights of the Child's requirement to include young children in decision‐making. In the context of ongoing discussion about young children's capacity to share their views and opinions about matters affecting them ...
Laura Lundy +3 more
wiley +1 more source

