Results 201 to 210 of about 2,505,569 (334)

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

Advanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao, Qinyuan Liu, Zhongwei Xin, Zhiyao Zhou, Mingjie Lin, Di Chen, Zhixing Hao, Yongyuan Chen, Wenxuan Wu, Shuyang Zhang, Xiaoke Chen, Xia Xu, Jinfan Li, Wei Lin, Yuhao Lu, Dang Wu, Pin Wu   +16 more
wiley   +1 more source

Evaluation of the HIV Case-Based Surveillance System in Dire Dawa City Administration, Ethiopia. A Descriptive Cross-Sectional Study. [PDF]

AIDS Res Treat
Hagos F, Kassahun A, Sisay A.
europepmc   +1 more source

282300 - Video Surveillance [PDF]

, 2015
Weatherbee, Stephanie L.
core   +1 more source

USP9X as a Candidate Mediator of Prenatal Aspirin‐Induced Ovarian Reserve Reduction in Offspring Mice

Advanced Science, EarlyView.
This study suggests that prenatal aspirin exposure is associated with reduced ovarian reserve in offspring, associated with HDAC1‐linked epigenetic downregulation of Usp9x as a candidate mechanism. These preclinical findings provide new insights into fetal‐origin ovarian disorders and contribute to the evidence base concerning aspirin's gestational ...
Yating Li, Caiyun Ge, Wai Yen Yim, Hui Feng, Tiancheng Wu, Lu Chen, Qiaohua Xiong, Shumin Pan, Mei Wang, Huijun Chen, Yuanzhen Zhang, Hui Wang   +11 more
wiley   +1 more source

Evaluation of Communicable Diseases Surveillance System Structure in Mosul City

, 2023
Yasir Younus, Mohammed Khalifa
openalex   +2 more sources

Dysfunctional TRIM31 of POMC Neurons Provokes Hypothalamic Injury and Peripheral Metabolic Disorder under Long‐Term Fine Particulate Matter Exposure

Advanced Science, EarlyView.
Particulate matter ≤2.5 µm (PM2.5) elevates risks of neurological and chronic metabolic diseases, but the underlying mechanisms linking PM2.5‐induced central nervous system (CNS) injury to metabolic dysfunction remain unclear. Hypothalamic pro‐opiomelanocortin‐expressing (POMC+) neurons regulate systemic metabolic homeostasis, and tripartite motif ...
Chenxu Ge, Jiamao Lin, Changsheng Yang, Chuanwang Miao, Fengxiang Li, Shuqiang Zhao, Lei Zou, Xuedong Teng, Lina Liu, Tingguang Li, Yan Sun, Qiang Li, Deshuai Lou, Linfeng Hu, Xi Liu, Gang Kuang, Jing Luo, Minxuan Xu, Minghui Chang, Jun Tan, Yanrong Ren, Bochu Wang   +21 more
wiley   +1 more source

Monitoring COVID-19 occurrence in a resource-limited setting - COVID-19 sentinel surveillance in Malawi. [PDF]

PLOS Glob Public Health
Ulaya G, Kabaghe A, Saussier C, MacLachlan E, Smith-Sreen J, Katumbi C, Bello G, Tafatatha T, Chaponda L, Mvula B, Kagoli M, Chilima B, Bitilinyu-Bangoh J, Chisuwo L, Babaye Y, Chitenje M, Bighignoli B, Bangara F, Namakhoma I, Chauma-Mwale A, O'Malley G, Mirkovic K, Wadonda-Kabondo N.   +22 more
europepmc   +1 more source

ASSESSMENT OF THE DEVELOPMENT OF DEFORMATIONS ON THE EARTH'S SURFACE WITHIN THE STEBNYTSKY POTASSIUM DEPOSIT MINE FIELD BY THE DATA OF HYDROGEOLOGICAL SURVEILLANCE

, 2023
Z. Z. Khevpa, V. Dolin, Eugene YAKOVLEV, Victor DOLIN, Eugene YAKOVLEV   +4 more
openalex   +2 more sources

ZNRD2 Mediated Nucleoprotein Aggregation Impairs Respiratory Syncytial Virus Replication

Advanced Science, EarlyView.
During RSV infection, nucleoprotein (N) forms RNA‐bound oligomers. The host protein ZNRD2 binds to these oligomers, promoting their transition into insoluble aggregates. These aggregates simultaneously sequester functional N to restrict viral production and disrupt chaperonin assembly quality control by interfering with ZNRD2's role as an adaptor ...
Haiwu Zhou, Mingbin He, Jinhong Du, Cong Liu, Weiwei Wang, Yuewen Han, Zhifei Li, Yali Qin, Mingzhou Chen   +8 more
wiley   +1 more source

Effectiveness of poliovirus environmental surveillance in Ghana: an indicator-based performance evaluation across seven regions, 2018-2022. [PDF]

BMJ Open
Obodai E, Asante Ntim NA, Duker EO, Gberbi E, Antwi CN, Mensah JY, Odame D, Boakye JD, Bimpong SA, Agbotse GD, Odoom N, Adams PL, Acquah NK, Dickson AE, Odoom C, Achempem KK, Baffoe-Nyarko I, Egbi G, Laryea D, Asiedu-Bekoe F, Odoom JK.   +20 more
europepmc   +1 more source