Results 211 to 220 of about 994,465 (248)

AI-driven strategies for enhancing Mpox surveillance and response in Africa

David B. Olawade, Chiamaka Norah Ezeagu, Chibuike S Alisi, Aanuoluwapo Clement David-Olawade, Deborah Motilayo Eniola, Temitope Akingbala, Ojima Z. Wada   +6 more
openalex   +1 more source

Smohaze‐Upregulated RFWD3 Competes with TRIM24 to Stabilize TREX1 and Reduce Cytosolic dsDNA in Non‐Small Cell Lung Cancer

Advanced Science, EarlyView.
The E3 ubiquitin ligase RFWD3 binds the exonuclease TREX1 and protects it from TRIM24‐mediated ubiquitination and degradation, leading to the eradication of intracellular dsDNA, inhibition of the cGAS‐STING pathway, and immunosuppressive microenvironment of lung cancer.
Xue‐Yan Shi, Yu‐Ke Shen, Meng‐Yao Lv, Yu Sun, Yong‐Fang Lin, Zheng Wang, Xiao‐Liang Jie, Zheng Liu, Yang‐Tong Liu, Yang‐Xin Fu, Zhenhua Ren, Gui‐Zhen Wang, Guang‐Biao Zhou   +12 more
wiley   +1 more source

Estimating dengue force of infection from age-stratified surveillance data in Java, Indonesia. [PDF]

J R Soc Interface
Djaafara B, Elyazar IRF, Surya A, Silalahi FSM, Handito A, Aryani D, Kamal M, Gunawan D, Hipokrates H, Nisa AK, Prianto E, Samad I, Sugiarto A, Thohir B, Clapham H, Mishra S.   +15 more
europepmc   +1 more source

Mental Health Surveillance and Promotion at Work: A Psychosocial Study with Employees of a Health Institution

Gilmar Antoniassi, Alessandro Pereira da Silva, A. Miguel Gomes   +2 more
openalex   +1 more source

Multiscale Construction, Evaluation, and Application of Organoids

Advanced Science, EarlyView.
Organoids are pivotal models with transformative biomedical potential. A comprehensive multi‐scale perspective is presented, encompassing dual‐scale construction, four‐dimensional evaluation, triple‐point application, and an analysis of the current challenges faced by organoid technology, aiming to advance organoid research and its biomedical ...
Wanting Ma, Zhenglin Dong, Zhu'anzhen Zheng, Long Bai, Xingcai Zhang, Jiacan Su   +5 more
wiley   +1 more source

Active surveillance of multidrug-resistant organism colonization in a tertiary hospital in Northern Greece. [PDF]

Sci Rep
Myrou A, Savvakis S, Kiouli C, Kachtsidis V, Papathanasiou E, Ouzouni S, Georgopoulou I, Metallidis S.   +7 more
europepmc   +1 more source

cGAS Inhibits ALDH2 to Suppress Lipid Droplet Function and Regulate MASLD Progression

Advanced Science, EarlyView.
cGAS is a cytosolic DNA sensor known for innate immune defense. cGAS binds and suppresses ALDH2 are showed, limiting acetyl‐CoA production. cGAS loss activates ALDH2, promoting histone acetylation, lipogenesis, and lipid droplets accumulation. cGas‐/‐ mice on a high‐fat diet show signs of worsened MASLD.
Ying Wang, Yu Deng, Jianfeng Chen, Quentin Hahn, David S. Umbaugh, Zhigang Zhang, Yanqiong Zhang, Sarah E. Rowe, Lupeng Li, Laura E. Herring, Brian P. Conlon, Edward A. Miao, Blossom Damania, Anna Mae Diehl, Pengda Liu   +14 more
wiley   +1 more source

Surveillance of infectious diseases spreading on time-varying multiplex networks. [PDF]

Infect Dis Model
Hu J, Zheng H, Cai Y, Kong Y, Wang Y, Sun GQ, Lv J, Liu QH.   +7 more
europepmc   +1 more source

Affective surveillance, bio-political governance, and CORPOREA’s postdigital interactive exhibits: a bio-semiotic forensic analysis

Nashwa Elyamany, Yasser El Shamy
openalex   +1 more source

Acetylation of the Mitochondrial Chaperone GRP75 Governs ER‐Mitochondrial Calcium Homeostasis and Hepatocyte Insulin Resistance

Advanced Science, EarlyView.
Overnutrition exacerbates insulin resistance (IR) and is linked to excessive mitochondrial protein acetylation. However, it remains unclear whether and how mitochondrial protein acetylation influences IR. GCN5L1‐dependent downregulation of GRP75 acetylation at K567/612 consequently enhances ER‐mitochondrial calcium flux and induces ER stress.
Danni Wang, Jiaqi Zhang, Xinyu Yang, Qiqi Zhang, Xiuya Hu, Xin Lu, Hanni Li, Xue Bai, Kai Zhang, Michael N. Sack, Yongsheng Chang, Yingmei Wang, Lingdi Wang, Lu Zhu   +13 more
wiley   +1 more source