Results 211 to 220 of about 2,418,550 (336)

Post-marketing surveillance of drugs. [PDF]

, 1979
A W Harcus, Andrea Ward, Dave Smith
openalex   +1 more source

Exploring Functionally Enhanced BLP‐Trained Macrophage Subpopulations in S. Aureus Infection: Underlying Mechanisms and Therapeutic Significance

Advanced Science, EarlyView.
BLP‐trained macrophages show augmented resistance to infection, but their mechanisms remain unclear. scRNA‐seq identified 13 BMDM subsets, with two novel anti‐inflammatory/antibacterial subpopulations (C5/C7) emerging post‐BLP training. BLP training activates NRF2, attenuates oxidative stress/ferroptosis, and boosts glycolysis/OXPHOS. Adoptive transfer
Yantong Wan, Yinghao Hong, Xiangjun Ji, Jing Xiang, Jinxi Liu, Lixin Liang, Meng Ren, Wenhan Chen, Tengfei Xu, Zhijie Li, Tieliu Shi, Yong Jiang, Huaping Liang, Jinghua Liu   +13 more
wiley   +1 more source

Ongoing increase in measles cases following importations, Japan, March 2014: times of challenge and opportunity

Western Pacific Surveillance and Response, 2014
Takuri Takahashi, Yuzo Arima, Hitomi Kinoshita, Kazuhiko Kanou, Takehito Saitoh, Tomimasa Sunagawa, Hiroaki Ito, Atsuhiro Kanayama, Ayako Tabuchi, Kazutoshi Nakashima, Yuichiro Yahata, Takuya Yamagishi, Tamie Sugawara, Yasushi Ohkusa, Tamano Matsui, Satoru Arai, Hiroshi Satoh, Keiko Tanaka-Taya, Katsuhiro Komase, Makoto Takeda, Kazunori Oishi   +20 more
doaj   +1 more source

How can timeliness and accuracy be balanced? The surveillance information reporting mechanism for public health emergencies based on the online direct reporting system. [PDF]

BMC Public Health
Song Y, Ma R, Liu J, Guo Y, An S.
europepmc   +1 more source

HERV‐K TM Subunit Elicits CD8+ T Cell Anergy and Tumor Immune Evasion via Targeting CD3 Coreceptor ε in AML and PDAC

Advanced Science, EarlyView.
Novel viral immune checkpoint K‐TM subunit is aberrantly expressed in CD8+ T cells and enriched in sera of cancer patients, inducing CD8+ T cell anergy and eliciting potent tumor immune escape in mouse model. Mechanistically, K‐TM directly targets and induces the phosphorylation of CD3ε receptor.
Mengyuan Li, Shuwen Zheng, Qinyuan Gong, Zhaoxing Wu, Wen Lei, Wanyue Cao, Ping Wang, Xuzhao Zhang, Wenbin Qian, Yun Liang, Ying Lu, Fenglin Li, Qi Zhang, Rongzhen Xu   +13 more
wiley   +1 more source

Systematic misclassification of sylvatic dengue virus 2 (DENV-2) infections as "undetermined serotype": implications in routine RT-qPCR surveillance. [PDF]

Trop Med Health
Dieng I.
europepmc   +1 more source

Hippocampal Chandelier Cells Modulate Seizure Susceptibility and Severity

Advanced Science, EarlyView.
The axon initial segment (AIS), crucial for action potential initiation, serves as a prime locus for controlling network activity. Chandelier Cells (ChCs), evolved in the mammals, intricately target AISs, acting as gatekeepers for neuronal firing. Diminishing ChC input makes animals more prone to developing seizures, whereas fortifying this connection ...
Yang Li, Jifeng Tian, Jiafan Wei, Qianyun Wang, Jiaxu Ge, Jianguang Ni, Jiangteng Lu, Yilin Tai   +7 more
wiley   +1 more source

Protocol for an observational cohort study integrating real-world data and microsimulation to assess imaging surveillance strategies in stage I-IIIA NSCLC patients in OneFlorida. [PDF]

BMJ Open
Braithwaite D, Karanth SD, Bian J, Meza R, Jeon J, Tammemagi M, Wheeler M, Cao P, Rackauskas M, Shrestha P, Yoon HA, Borondy Kitts A, Verma H, Blair MC, Chen A, Das D, Lou X, Wu Y, Han S, Hochhegger B, Guo Y, Gould MK.   +21 more
europepmc   +1 more source

Surveillance of fatal motor vehicle accidents in michigan, involving young drivers, utilizing time-series analysis of police records [PDF]

, 1971
Stanley H. Schuman, M. Anthony Schork, Songsee Srivannaboon   +2 more
openalex   +1 more source

The Pathogenic Roles of Local Vitamin D Metabolism Defect in Valve Inflammation and Calcification

Advanced Science, EarlyView.
This study identifies the valvular interstitial cell populations responsible for valvular calcification induced by hyperphosphatemia and likely aging, uncovers local vitamin D metabolism defect‐induced inflammation as a critical pathogenic factor of calcific aortic valve disease, and highlights active vitamin D and ERK inhibitor as potential preventive
Ruichen Yang, Chong Han, Yangli Xie, Shoutao Qiu, Shaoyang Zhang, Jingjia He, Zejian Wang, Zhenlin Zhang, Huijuan Liu, Lin Chen, Baojie Li   +10 more
wiley   +1 more source