Results 261 to 270 of about 2,336,472 (333)

KRAS mRNA Spleen‐Targeting Lipid Nanoparticles Synergize with Irinotecan Silicasomes to Robustly Augment the Cancer Immunity Cycle in Pancreatic Cancer

Advanced Science, EarlyView.
To overcome pancreatic cancer's immunosuppressive barriers, this study explores a dual approach: triggering immunogenic tumor cell death at the primary tumor site with irinotecan‐loaded silicasomes and enhancing immune activation in the spleen using LNPs encapsulating tumor antigen mRNA and a TLR7/8 agonist.
Lijia Luo, Xiang Wang, Yu‐Pei Liao, Andre E. Nel   +3 more
wiley   +1 more source

Assessing early detection ability through spatial arrangements in environmental surveillance for poliovirus: A simulation-based study. [PDF]

PLoS One
Asakura TR, O'Reilly KM.
europepmc   +1 more source

[Chagas' disease. Entomological surveillance activities developed in an area of the State of São Paulo, Brazil].

, 1970
E O da Rocha e Silva, José Maluf, Renato de R. Corrêa   +2 more
openalex  

Cryo‐Inactivated Cancer Cells Derived Magnetic Micromotors for Tumor Immunotherapy

Advanced Science, EarlyView.
Cryo‐inactivated cancer cell‐based magnetic micromotors are developed for synergistic tumor immunotherapy via magnetic targeting. These micromotors can induce ferroptosis and immunogenic cell death, deliver tumor antigens, and activate the Mn2+‐dependent cGAS‐STING pathway. The system effectively suppresses tumor progression, recurrence, and metastasis,
Qingfei Zhang, Gaizhen Kuang, Wenzhao Li, Yuanjin Zhao   +3 more
wiley   +1 more source

The Immune Microenvironment: New Therapeutic Implications in Organ Fibrosis

Advanced Science, EarlyView.
This review summarizes recent advances in understanding the immune microenvironment's role in fibrosis, focusing on phenotypic/functional alterations of immune cells and their dynamic interactions with other cellular constituents within tissues. The authors further explore therapeutic opportunities and challenges in targeting immune microenvironment ...
Xiangqi Chen, Chuan Wu, Fei Tang, Jingyue Zhou, Li Mo, Yanping Li, Jinhan He   +6 more
wiley   +1 more source

The future of healthcare-associated infection surveillance: Automated surveillance and using the potential of artificial intelligence. [PDF]

J Intern Med
van der Werff SD, van Rooden SM, Henriksson A, Behnke M, Aghdassi SJS, van Mourik MSM, Nauclér P.   +6 more
europepmc   +1 more source

DRUG SURVEILLANCE FOR ADVERSE DRUG EFFECTS A STUDY OF MEDICAL INPATIENTS

, 1978
David H. Lawson, Hershel Jick
openalex   +1 more source

API5 Phosphorylation Promotes Antiviral Immunity by Inhibiting Degradation of Cytosolic RNA Sensor RLRs

Advanced Science, EarlyView.
Ubiquitin‐mediated selective autophagy plays a critical role in antiviral innate immunity. The study shows that upon RNA virus infection, cytoplasmic API5 undergoes SRPK1‐dependent phosphorylation at S464, which in turn suppresses p62 K141 ubiquitination‐dependent autophagy.
Tingjuan Deng, Jianan Xu, Linglong Qin, Xingbo Wang, Chenhe Lu, Yanming Huang, Da Liu, Yan Yan, Weiren Dong, Pinglong Xu, Jiyong Zhou   +10 more
wiley   +1 more source

Artificial intelligence in early warning systems for infectious disease surveillance: a systematic review. [PDF]

Front Public Health
Villanueva-Miranda I, Xiao G, Xie Y.
europepmc   +1 more source

REPORT OF OFF-SITE SURVEILLANCE FOR PROJECT CABRIOLET.

, 1971

openalex   +2 more sources