Results 161 to 170 of about 1,037,391 (301)

Applying a systems thinking approach to evaluating the effectiveness of Africa's foodborne disease surveillance systems. [PDF]

Commun Med (Lond)
Thystrup C, Ogunbiyi T, Hald T.
europepmc   +1 more source

Allogeneic Immune Cell Perfusion Inhibits the Growth of Vascularized 3D In Vitro Tumor Models, Induces Vascular Regression and Desmoplasia, but Promotes Tumor Cell Invasion

Advanced Science, EarlyView.
This study presents a vascularized 3D tumor model to investigate immune–stromal–tumor interactions under allogeneic PBMC perfusion. While immune cells induced tumor shrinkage, they also promoted vascular regression, stromal activation, and cancer cell invasion.
Alexandra Raab, Rasika Daware, Marcelo A. Szymanski de Toledo, Oskar Weber, Dimitris Kapsokalyvas, Twan Lammers, Horst Fischer, Federica De Lorenzi, Fabian Kiessling   +8 more
wiley   +1 more source

Surveillance System

Japanese Journal of Medical Science and Biology, 1998
openaire   +2 more sources

Paving the Way to Elucidate Hg's Role in Tumorigenesis

Advanced Science, EarlyView.
Tumorigenesis can result from diverse environmental carcinogens. Among them, mercury—a lifelong bioaccumulative Group 2B carcinogen—has tumorigenic potential that remains poorly understood due to confounding co‐exposures and limited organ‐specific data.
Shouying Li, Rong Zhong, Zhenyang Yu, Hualing Fu, Jin Chen, Jia Wei, Ningwei Zhao, Le Qu, Tiantian Li, Wenli Tang, Huan Zhong   +10 more
wiley   +1 more source

A Systematic Review of New, Enhanced Surveillance Systems and Methodologies for Zoonotic Influenza Viruses in Animals and Human-Animal Interface. [PDF]

Influenza Other Respir Viruses
Badra R, Zhang W, Tam JSL, Webby R, Van Der Werf S, Nikisins S, Cullinane A, Gharaibeh S, Njouom R, Peiris M, Kayali G, Heraud JM.   +11 more
europepmc   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

Expanding National-Scale Wildlife Disease Surveillance Systems With Research Networks. [PDF]

Ecol Evol
Pepin KM, Combs MA, Bastille-Rousseau G, Craft ME, Cross P, Diuk-Wasser MA, Gagne RB, Gallo T, Garwood T, Heale JD, Hewitt J, Høy-Petersen J, Malmberg J, Mullinax J, Plimpton L, Smith L, VanAcker MC, Chandler JC, Walter WD, Wilson-Henjum G, Wittemyer G, Manlove K.   +21 more
europepmc   +1 more source

Understanding and Overcoming Antibody‐Drug Conjugate Resistance: Biological Mechanisms and Emerging Analytical Frameworks in Breast Cancer

Advanced Science, EarlyView.
Antibody–drug conjugates (ADCs) transform breast cancer therapy, yet resistance limits their durability. Emerging evidence reveals that ADC failure is not solely tumor‐intrinsic but shaped by dynamic tumor–microenvironment interactions that alter drug delivery, processing, and response.
Minji Seo, Jangsoon Lee, Naoto T. Ueno
wiley   +1 more source

Decoding Triphenotypic Neutrophils in Cervical Cancer Evolution and Targeting SPP1+/GBP1+/ELOVL5+ Tumor‐Associated Neutrophils to Sensitize Immunotherapy

Advanced Science, EarlyView.
The functional schematic diagram of tumor associated neutrophils. Abstract Enhancing cervical cancer (CC) immunotherapy requires deciphering the heterogeneous tumor immune microenvironment (TIME), particularly neutrophil phenotypic dynamics. Here, 1) we collected 543 CC cases to find that patients with elevated neutrophil levels have a higher incidence
Xingyu Chang, Xinyu Qu, Tingting Ren, Tong Wu, Weiyong Gu, Jingxin Ding, Keqin Hua, Junjun Qiu   +7 more
wiley   +1 more source

Cohort Profile: Hodal and Lowairpoa Demographic Surveillance Systems. [PDF]

Int J Epidemiol
Sharma N, Rajitha P ET, Varghese S, Krishnamoorthy DK, Jadaun AS, Koshy RM, Vats P, Raj RB, Srinivasan R, Raghava Mohan V, Mazumder S.   +10 more
europepmc   +1 more source