Results 241 to 250 of about 3,324,864 (354)

Protocol for evaluation of Movember's scaling what works grant funding program: Supporting the delivery of mental health interventions for men & boys in Australia, Canada and the United Kingdom. [PDF]

PLoS One
Steele T, Ang C, Rose V, Kembhavi G, Rowland J, Abdo M, Kwok J, Young K, Merryfull S, Whittaker S, Brusco N, Watt R, Büsst C.   +12 more
europepmc   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Let's Talk aBOT Scam Online Survey Completions in Health Behavior Research: Tutorial With Case Studies, Practical Guidance, and a Checklist for Researchers.

JMIR Public Health Surveill
Arundell L, Salmon J, Walsh A, Dullaghan K, Cheng H, Baker T, Teychenne M, Schuch F, Tornquist D, Timperio A.   +9 more
europepmc   +1 more source

A cross-sectional survey of reproductive, gynecological, and breast health histories and status among people in a provincial prison for women in British Columbia. [PDF]

PLoS One
Heggie C, Paynter M, McLeod A, Liauw J, Edwards R, Kouyoumdjian F.   +5 more
europepmc   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

A Complex Digital Health Intervention to Support People With HIV: Organizational Readiness Survey Study and Preimplementation Planning for a Hybrid Effectiveness-Implementation Study.

J Med Internet Res
Hodges J, Cohn W, Castel A, Flickinger T, Waldman AL, Hilgart M, Kirby O, Caldwell S, Ingersoll K.   +8 more
europepmc   +1 more source

Data collected for the Child Health and Mortality Prevention Surveillance (CHAMPS) network evaluating the impact of COVID-19 lockdown protocol in Karemo - Siaya and Manyatta - Kisumu, Kenya. [PDF]

Data Brief
Obor D, Muir JA, Munga S, Barr BT, Onyango D, Khaggayi C, Owiti L, Asuke B, Achayo E, Odhiambo BA, Aol G, Misore T, Abong'o N, Madewell ZJ, Cunningham SA, Akelo V.   +15 more
europepmc   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

A national study of substance use: Demonstrated use of recommendations for best practice online data collection. [PDF]

PLoS One
Bontemps AP, Pridgen BE, Wagner WP, Cropsey KL.   +3 more
europepmc   +1 more source

New documentary data from the Geominero Museum (the Spanish Geological Survey, Madrid) on the archaeocyathan collection from the Ermitas Hill of Cordoba

, 2014
A. Perejón, S. Menéndez, I. Rábano, E. Moreno-Eiris   +3 more
openalex   +2 more sources